Leadership In Controlled Gene Expression


Aceto, N. Balwierz, P. J. Bentires-Alj, M. Brinkhaus, H. Confalonieri, S. Elledge, S. J. Gaidatzis, D. Hu, G. Martiny-Baron, G. Mazzarol, G. Pachkov, M. Quarto, M. Sausgruber, N. Stadler, M. B. van Nimwegen, E. (2012) Tyrosine phosphatase SHP2 promotes breast cancer progression and maintains tumor-initiating cells via activation of key transcription factors and a positive feedback signaling loop. Nat Med 529-37


Acharyya, S. Brogi, E. Hogg, N. Kim, J. Leversha, M. Malladi, S. Manova-Todorova, K. Massague, J. Morris, P. G. Norton, L. Oskarsson, T. Seshan, V. E. Vanharanta, S. (2012) A CXCL1 paracrine network links cancer chemoresistance and metastasis. Cell 165-78


Adair-Kirk, T. L. Griffin, G. L. Keene, D. R. Kelley, D. G. Marinkovich, M. P. Meyer, M. J. Miner, J. H. Ruppert, J. M. Senior, R. M. Uitto, J. (2012) Keratinocyte-targeted expression of human laminin gamma2 rescues skin blistering and early lethality of laminin gamma2 deficient mice. PLoS One e45546


Adeyemi, Richard O. Pintel, David J. (2012) Replication of Minute Virus of Mice in Murine Cells Is Facilitated by Virally Induced Depletion of p21. Journal of Virology 8328-8332


Afelik, Solomon Bukys, Michael A. Deering, Tye Hasrouni, Edy Jensen, Jan MacDonald, Raymond J. Nieuwoudt, Stephan Qu, Xiaoling Rogers, William (2012) Notch-mediated patterning and cell fate allocation of pancreatic progenitor cells. Development 1744-1753


Aggarwal, A. Cunningham, A. L. Iemma, T. L. McAllery, S. Newsome, T. P. Shih, I. Turville, S. G. (2012) Mobilization of HIV spread by diaphanous 2 dependent filopodia in infected dendritic cells. PLoS Pathog e1002762


Ahfeldt, T. Al-Siddiqi, H. Camahort, R. Clish, C. B. Cowan, C. A. Cowley, A. Deo, R. C. Gerszten, R. E. Hendrickson, D. Kaplan, A. Lau, F. H. Lee, Y. K. Lum, D. H. Mowrer, G. Musunuru, K. Nahrendorf, M. Rhee, E. P. Rinn, J. L. Schinzel, R. T. Shay, J. Shen, T. Xia, F. (2012) Programming human pluripotent stem cells into white and brown adipocytes. Nat Cell Biol 209-19


Ajay, A. K. Bhat, M. K. Meena, A. S. (2012) Human papillomavirus 18 E6 inhibits phosphorylation of p53 expressed in HeLa cells. Cell Biosci 2


Ajayi, A. Langel, U. Lindberg, S. Strom, A. L. Yu, X. (2012) Expanded ataxin-7 cause toxicity by inducing ROS production from NADPH oxidase complexes in a stable inducible Spinocerebellar ataxia type 7 (SCA7) model. BMC Neurosci 86


Akki, Ashwin Chacko, Vadappuram P. Gupta, Ashish Leppo, Michelle K. Steenbergen, Charles Su, Jason Wang, Yibin Weiss, Robert G. Yano, Toshiyuki (2012) Creatine kinase overexpression improves ATP kinetics and contractile function in postischemic myocardium. Am J Physiol Heart Circ Physiol H844-852


Aksoy, Ozlem Chicas, Agustin Lowe, Scott W. McCurrach, Mila Wang, Xiaowo Zeng, Tianying Zhao, Zhen (2012) The atypical E2F family member E2F7 couples the p53 and RB pathways during cellular senescence. Genes & Development 1546-1557


Alevy, Y. G. Brett, T. J. Byers, D. E. Heier, R. F. Holtzman, M. J. Miller, C. A. Patel, A. C. Patel, D. A. Romero, A. G. Roswit, W. T. Tucker, J. (2012) IL-13-induced airway mucus production is attenuated by MAPK13 inhibition. J Clin Invest 4555-68


Alhebshi, Alawiah Avery, Simon V. Holland, Sara L. Sideri, Theodora C. (2012) The essential iron-sulfur protein Rli1 is an important target accounting for inhibition of cell growth by reactive oxygen species. Mol. Biol. Cell 3582-3590


Alimperti, S. Andreadis, S. T. Lei, P. Tian, J. (2012) A novel lentivirus for quantitative assessment of gene knockdown in stem cell differentiation. Gene Ther


Al-Owais, Moza M. A. Boycott, Hannah E. Boyle, John P. Chakrabarty, Aruna Dallas, Mark L. Peers, Chris Scragg, Jason L. Warburton, Philip (2012) Carbon Monoxide Mediates the Anti-apoptotic Effects of Heme Oxygenase-1 in Medulloblastoma DAOY Cells via K+ Channel Inhibition. Journal of Biological Chemistry 24754-24764


Al-Saif, M. Khabar, K. S. (2012) UU/UA dinucleotide frequency reduction in coding regions results in increased mRNA stability and protein expression. Mol Ther 954-9


Amoasii, L. Bertazzi, D. L. Chicanne, G. Cowling, B. S. Ferry, A. Friant, S. Hnia, K. Klaholz, B. Laporte, J. Payrastre, B. Rinaldi, B. Tronchere, H. (2012) Phosphatase-dead myotubularin ameliorates X-linked centronuclear myopathy phenotypes in mice. PLoS Genet e1002965


An, Xiaojin Cully, Brittany L. Duffy, Heather S. He, Ping Jin, Yi Li, Jian Messmer-Blust, Angela Philbrick, Melissa J. Song, Xiaoxiao Wu, Jiaping Xu, Ming (2012) Endothelial Cells Require Related Transcription Enhancer Factor-1 for Cell?ÄìCell Connections Through the Induction of Gap Junction Proteins. Arteriosclerosis, Thrombosis, and Vascular Biology 1951-1959


Anders, K. Blankenstein, T. Buschow, C. Charo, J. (2012) Depot formation of doxycycline impairs Tet-regulated gene expression in vivo. Transgenic Res 1099-107


Andrique, La?´titia Colasson, H?©l?®ne El Maassarani, Mahmoud Fauvin, Dominique S?©it?©, Paule Vannier, Brigitte (2012) ErbB380 kDa, a nuclear variant of the ErbB3 receptor, binds to the Cyclin D1 promoter to activate cell proliferation but is negatively controlled by p14ARF. Cellular Signalling 1074-1085


Angenieux, C. de la Salle, H. Gachet, C. Gidon, A. Hanau, D. Hojeij, R. Proamer, F. Salamero, J. Signorino-Gelo, F. Van Dorsselaer, A. Waharte, F. Wurtz, V. (2012) Lysosomal-Associated Transmembrane Protein 5 (LAPTM5) Is a Molecular Partner of CD1e. PLoS One e42634


Alvarez, J. Anguera, M. C. Gimelbrant, A. Haggarty, S. J. Kirby, J. E. Kwok, S. Lee, J. T. Mitalipova, M. Payer, B. Sadreyev, R. Sheridan, S. D. Sur, M. Szanto, A. Zhang, Z. (2012) Molecular signatures of human induced pluripotent stem cells highlight sex differences and cancer genes. Cell Stem Cell 75-90


Alphey, L. Ant, T. Economopoulos, A. Gong, H. F. Koukidou, M. Rempoulakis, P. Vontas, J. (2012) Control of the olive fruit fly using genetics-enhanced sterile insect technique. BMC Biol 51


Antonica, F. Costagliola, S. Dumitrescu, A. M. Iacovino, M. Kasprzyk, D. F. Kyba, M. Liao, X. H. Manto, M. Opitz, R. Peremans, K. Refetoff, S. (2012) Generation of functional thyroid from embryonic stem cells. Nature 66-71


Antoun, Ghadi Cannon, Pascale Bouchard Cheng, Hai-Ying Mary (2012) Regulation of MAPK/ERK Signaling and Photic Entrainment of the Suprachiasmatic Nucleus Circadian Clock by Raf Kinase Inhibitor Protein. The Journal of Neuroscience 4867-4877


Aoki, Hitomi Era, Takumi Hara, Akira Kunisada, Takahiro Yamada, Yasuhiro (2012) Genetic ablation of Rest leads to in vitro-specific derepression of neuronal genes during neurogenesis. Development 667-677


Aono, Yoshinori Beers, Michael F. Ledford, Julie G. Mukherjee, Sambuddho Nishioka, Yasuhiko Noble, Paul W. Ogawa, Hirohisa Sone, Saburo Wright, Jo Rae (2012) Surfactant Protein-D Regulates Effector Cell Function and Fibrotic Lung Remodeling in Response to Bleomycin Injury. Am. J. Respir. Crit. Care Med. 525-536


Akasaki, Yuichi Araki, Satoshi Hanatani, Shinsuke Izumiya, Yasuhiro Nakagata, Naomi Ogawa, Hisao Rokutanda, Taku Takeo, Toru Usuku, Hiroki Walsh, Kenneth (2012) Akt1?ÄìMediated Skeletal Muscle Growth Attenuates Cardiac Dysfunction and Remodeling After Experimental Myocardial Infarction / Clinical Perspective. Circulation: Heart Failure 116-125


Araki, Toshiyuki Arima, Kunimasa Kaido, Misako Nagano, Seiichi Ogata, Katsuhisa Tateno, Minako (2012) Misfolded SOD1 forms high-density molecular complexes with synaptic molecules in mutant SOD1-linked familial amyotrophic lateral sclerosis cases. Journal of the Neurological Sciences 92-96


Angelastro, J. M. Arias, A. Greene, L. A. Hen, R. Lame, M. W. Santarelli, L. (2012) Regulated ATF5 loss-of-function in adult mice blocks formation and causes regression/eradication of gliomas. Oncogene 739-51


Armakola, M. Barmada, S. J. Diaz, Z. Fang, X. Farese, R. V., Jr. Figley, M. D. Finkbeiner, S. Gitler, A. D. Higgins, M. J. Krogan, N. J. Scarborough, E. A. Shorter, J. (2012) Inhibition of RNA lariat debranching enzyme suppresses TDP-43 toxicity in ALS disease models. Nat Genet 1302-9


Arora, Rajika Azzalin, Claus M. Brun, Catherine M. (2012) Transcription regulates telomere dynamics in human cancer cells. RNA 684-693


Arslan, Ahmet Dirim Beck, William T. He, Xiaolong Rong, Lijun Rumschlag-Booms, Emily Wang, Minxiu (2012) A High-Throughput Assay to Identify Small-Molecule Modulators of Alternative Pre-mRNA Splicing. J Biomol Screen 1087057112459901


Artemenko, Yulia Batsios, Petros Borleis, Jane Devreotes, Peter N. Gagnon, Zachary Lee, Josephine Rohlfs, Meino Sans?©au, Doriane Schleicher, Michael Willard, Stacey S. (2012) Tumor suppressor Hippo/MST1 kinase mediates chemotaxis by regulating spreading and adhesion. Proceedings of the National Academy of Sciences 13632-13637


Aumiller, Jared J Hillar, Alexander Jarvis, Donald L Mabashi-Asazuma, Hideaki Shi, Xianzong (2012) A new glycoengineered insect cell line with an inducibly mammalianized protein N-glycosylation pathway. Glycobiology 417-428


Auriemma, L. B. Henriksen, M. A. Linden, L. M. Shah, S. (2012) Knockdown of menin affects pre-mRNA processing and promoter fidelity at the interferon-gamma inducible IRF1 gene. Epigenetics Chromatin 2


Ayer, A. Dawes, I. W. Fellermeier, S. Fife, C. Li, S. S. Meyer, A. J. Perrone, G. G. Smits, G. (2012) A genome-wide screen in yeast identifies specific oxidative stress genes required for the maintenance of sub-cellular redox homeostasis. PLoS One e44278


Babar, Imran A. Booth, Carmen J. Cheng, Christopher J. Liang, Xianping Saltzman, W. Mark Slack, Frank J. Weidhaas, Joanne B. (2012) Nanoparticle-based therapy in an in vivo microRNA-155 (miR-155)-dependent mouse model of lymphoma. Proceedings of the National Academy of Sciences E1695-E1704


Badea, Tudor Constantin Motajo, Oluwaseyi Nathans, Jeremy Shi, Melody Smallwood, Philip Williams, John (2012) Combinatorial Expression of Brn3 Transcription Factors in Somatosensory Neurons: Genetic and Morphologic Analysis. The Journal of Neuroscience 995-1007


Antony, Claude Arnold, Marc Bahtz, Ramona Haselmann-Weiss, Uta Hoffmann, Ingrid Lehmann, Wolf D. Seidler, Joerg (2012) GCP6 is a substrate of Plk4 and required for centriole duplication. Journal of Cell Science 486-496


Arzigian, Melanie Bai, Hao Chen, Kang Gao, Yong-Xing Malcosky, Christopher Wang, Zack Z. Wu, Wen-Shu Xie, Yin-Liang Yang, Yong-Guang (2012) Bcl-xL enhances single-cell survival and expansion of human embryonic stem cells without affecting self-renewal. Stem Cell Research 26-37


Anders, Robert A. Argani, Pedram Bai, Haibo Gayyed, Mariana F. Khan, Mehtab Klein, Alison P. Lam-Himlin, Dora M. Nayar, Suresh K. Pan, Duojia Xu, Yang (2012) Expression of Yes-associated protein modulates Survivin expression in primary liver malignancies. Human Pathology 1376-1385


Baik, J. Borges, L. Magli, A. Perlingeiro, R. C. Thatava, T. (2012) Effect of endoglin overexpression during embryoid body development. Exp Hematol 837-46


Bajaj, A. Li, Q. F. Pumiglia, K. Zheng, Q. (2012) Loss of NF1 expression in human endothelial cells promotes autonomous proliferation and altered vascular morphogenesis. PLoS One e49222


Bakker, Elvira R. M. Franken, Patrick F. Helvensteijn, Werner Kuipers, Ernst J. Meijlink, Frits Raghoebir, Lalini Rottier, Robbert J. Smits, Ron van der Valk, Martin A. van Gurp, L?©on van Veelen, Wendy (2012) Induced Wnt5a expression perturbs embryonic outgrowth and intestinal elongation, but is well-tolerated in adult mice. Developmental Biology 91-100


Arteaga, Carlos L. Balko, Justin M. Cook, Rebecca S. Hutchinson, Katherine Jee, David Miller, Todd W. Morrison, Meghan M. Perou, Charles M. Polyak, Kornelia Prat, Aleix Rinehart, Cammie S?°nchez, Violeta Young, Christian (2012) The receptor tyrosine kinase ErbB3 maintains the balance between luminal and basal breast epithelium. Proceedings of the National Academy of Sciences 221-226


Banakh, I. Gonez, L. J. Harrison, L. C. Naselli, G. Sutherland, R. M. (2012) Adult pancreas side population cells expand after beta cell injury and are a source of insulin-secreting cells. PLoS One e48977


Amori, Ilaria Banci, Lucia Bertini, Ivano Bla?æevit?°, Olga Calderone, Vito Cantini, Francesca Carr?¨, Maria Teresa Cozzolino, Mauro Mao, Jiafei Trapananti, Angela Vieru, Miguela (2012) Interaction of Cisplatin with Human Superoxide Dismutase. Journal of the American Chemical Society 7009-7014


Bannerman, D. M. Bus, T. Hvalby, O. Jensen, V. Rawlins, J. N. Sanderson, D. J. Schwarz, I. Seeburg, P. H. Sprengel, R. Taylor, A. (2012) Dissecting spatial knowledge from spatial choice by hippocampal NMDA receptor deletion. Nat Neurosci


Bardai, Farah H. D'Mello, Santosh R. Price, Valerie Wang, Lulu Zaayman, Marcus (2012) Histone Deacetylase-1 (HDAC1) Is a Molecular Switch between Neuronal Survival and Death. Journal of Biological Chemistry 35444-35453


Alphey, Luke Bargielowski, Irka Kaufmann, Christian Koella, Jacob Reiter, Paul (2012) Flight Performance and Teneral Energy Reserves of Two Genetically-Modified and One Wild-Type Strain of the Yellow Fever Mosquito Aedes aegypti. Vector-Borne and Zoonotic Diseases 1053-1058


Barnes, J. M. Henry, M. D. Nauseef, J. T. (2012) Resistance to fluid shear stress is a conserved biophysical property of malignant cells. PLoS One e50973


Albright, Charles F. Andorfer, Cathy Barten, Donna M. Cadelina, Gregory W. DeCarr, Lynn B. Fanara, Patrizia Fessler, Chancy Gray, Gemma Hanna, Amanda Hoque, Nina Husted, Kristofor H. Janus, Christopher G. Kim, Soong-Hoon Lee, Francis Y. Liu, Victoria Meredith, Jere E. Olson, Richard E. Polson, Craig Protassio, Joan Riff, Timothy Sankaranarayanan, Sethu Turner, Holly Vite, Gregory D. Wong, P. Y. Anne Yang, Ling (2012) Hyperdynamic Microtubules, Cognitive Deficits, and Pathology Are Improved in Tau Transgenic Mice with Low Doses of the Microtubule-Stabilizing Agent BMS-241027. The Journal of Neuroscience 7137-7145


Basso, Katia Dalla-Favera, Riccardo Holmes, Antony B. Leslie, Christina Schneider, Christof Setty, Manu Shen, Qiong (2012) BCL6 positively regulates AID and germinal center gene expression via repression of miR-155. J. Exp. Med. 2455-2465


Baudouin, Stephane J. De Zeeuw, Chris I. Gaudias, Julien Gerharz, Stefan Hatstatt, Laetitia Hen, Rene Punnakkal, Pradeep Scheiffele, Peter Spooren, Will Tanaka, Kenji F. Vogt, Kaspar Zhou, Kuikui (2012) Shared Synaptic Pathophysiology in Syndromic and Nonsyndromic Rodent Models of Autism. Science 128-132


Bauernfeind, Franz Hornung, Veit Knolle, Percy A. Rieger, Anna Schildberg, Frank A. Schmid-Burgk, Jonathan L. (2012) NLRP3 Inflammasome Activity Is Negatively Controlled by miR-223. The Journal of Immunology 4175-4181


Bayasula, Goto, Maki Iwase, Akira Kikkawa, Fumitaka Kiyono, Tohru Kobayashi, Hiroharu Kondo, Mika Kotani, Tomomi Manabe, Shuichi Nagatomo, Yoshinari Nakahara, Tatsuo Nakamura, Tomoko Takikawa, Sachiko (2012) Establishment of a Human Nonluteinized Granulosa Cell Line that Transitions from the Gonadotropin-Independent to the Gonadotropin-Dependent Status. Am J Physiol Renal Physiol F1362-1373


Adler, Aaron Appleton, Evan Babb, Jonathan Beal, Jacob Bhatia, Swapnil Davidsohn, Noah Densmore, Douglas Haddock, Traci Loyall, Joseph Schantz, Richard Vasilev, Viktor Weiss, Ron Yaman, Fusun (2012) An End-to-End Workflow for Engineering of Biological Networks from High-Level Specifications. ACS Synthetic Biology 317-331


Bedard, Kristin M. Gale, Michael Iadonato, Shawn P. Katze, Michael G. Loo, Yueh-Ming Proll, Sean C. Wang, Myra L. (2012) Isoflavone Agonists of IRF-3 Dependent Signaling Have Antiviral Activity against RNA Viruses. Journal of Virology 7334-7344


Begus-Nahrmann, Y. Eshraghi, P. Grieb, M. Hartmann, D. Kestler, H. A. Kraus, J. Lechel, A. Lee, H. W. Rasche, V. Rudolph, K. L. Scheffold, A. Schirmacher, P. (2012) Transient telomere dysfunction induces chromosomal instability and promotes carcinogenesis. J Clin Invest 2283-8


Belguise, K. Chalbos, D. Galtier, F. Milord, S. Moquet-Torcy, G. Piechaczyk, M. (2012) The PKCtheta pathway participates in the aberrant accumulation of Fra-1 protein in invasive ER-negative breast cancer cells. Oncogene


Bepari, A. K. Nambu, A. Sano, H. Takebayashi, H. Tamamaki, N. Tanaka, K. F. (2012) Identification of optogenetically activated striatal medium spiny neurons by npas4 expression. PLoS One e52783


Adams, David J. Been, Raha A. Bergerson, Rachel J. Collier, Lara S. Delwel, Ruud Diers, Miechaleen D. Fan, Danhua Kersey, John H. Kogan, Scott C. Lamblin, Anne-Francoise J. Largaespada, David A. Lowe, Scott W. Lugthart, Sanne Nixon, Molly J. O'Sullivan, M. Gerard Rappaport, Amy R. Sarver, Aaron L. Silverstein, Kevin A. T. Wolff, Linda Zuber, Johannes (2012) An insertional mutagenesis screen identifies genes that cooperate with Mll-AF9 in a murine leukemogenesis model. Blood 4512-4523


Bergmann, Jan H. Earnshaw, William C. Jakubsche, Julia N. Kagansky, Alexander Kelly, David A. Kimura, Hiroshi Larionov, Vladimir Martins, Nuno M. Masumoto, Hiroshi Nakano, Megumi Turner, Bryan M. (2012) Epigenetic engineering: histone H3K9 acetylation is compatible with kinetochore structure and function. Journal of Cell Science 411-421


Bartel, David P. Bernstein, Douglas A. Drinnenberg, Ines A. Fink, Gerald R. Vyas, Valmik K. Weinberg, David E. (2012) Candida albicans Dicer (CaDcr1) is required for efficient ribosomal and spliceosomal RNA maturation. Proceedings of the National Academy of Sciences 523-528


Betney, Russell de Silva, Eric Knox, Yvonne Krishnan, J. Mertens, Christina Stansfield, Ian (2012) Regulation of release factor expression using a translational negative feedback loop: A systems analysis. RNA 2320-2334


Beverly, Levi J. Erdjument-Bromage, Hediye Lockwood, William W. Shah, Parag P. Varmus, Harold (2012) Ubiquitination, localization, and stability of an anti-apoptotic BCL2-like protein, BCL2L10/BCLb, are regulated by Ubiquilin1. Proceedings of the National Academy of Sciences E119-E126


Bhattarai, Nirjal Kaufman, Thomas M. McLinden, James H. Stapleton, Jack T. Xiang, Jinhua (2012) GB Virus C Envelope Protein E2 Inhibits TCR-Induced IL-2 Production and Alters IL-2?ÄìSignaling Pathways. The Journal of Immunology 2211-2216


Aiyar, R. S. Bietenhader, M. Clauder-Munster, S. Contamine, V. Denmat, S. H. Dequard-Chablat, M. di Rago, J. P. Gagneur, J. Giraud, M. F. Godard, F. Kucharczyk, R. Martos, A. Sagot, I. Sainsard-Chanet, A. Salin, B. Sellem, C. H. Steinmetz, L. M. Tetaud, E. (2012) Experimental Relocation of the Mitochondrial ATP9 Gene to the Nucleus Reveals Forces Underlying Mitochondrial Genome Evolution. PLoS Genet e1002876


Amici, A. Bisaro, B. Cabodi, S. Camacho-Leal, M. P. Camporeale, A. Colombo, S. M. Defilippi, P. Di Stefano, P. Galie, M. Iezzi, M. Konstantinidou, G. Marchini, C. Montani, M. Orso, F. Pietrella, L. Taverna, D. Tornillo, G. Turco, E. (2012) p130Cas/Cyclooxygenase-2 axis in the control of mesenchymal plasticity of breast cancer cells. Breast Cancer Res R137


Bisht, Kamlesh K. Chang, William G. Dudognon, Charles Ramirez, Alejandro Smith, Susan Sokol, Ethan S. (2012) GDP-Mannose-4,6-Dehydratase Is a Cytosolic Partner of Tankyrase 1 That Inhibits Its Poly(ADP-Ribose) Polymerase Activity. Molecular and Cellular Biology 3044-3053


Blagbrough, Ian S. Ghonaim, Hassan M. Metwally, Abdelkader A. (2012) Asymmetrical N4,N9-Diacyl Spermines: SAR Studies of Nonviral Lipopolyamine Vectors for Efficient siRNA Delivery with Silencing of EGFP Reporter Gene. Molecular Pharmaceutics 1853-1861


Blondeau, B. Breant, B. Dorchene, D. Jaisser, F. Massourides, E. Sahly, I. Singh-Estivalet, A. Tronche, F. Valtat, B. (2012) Novel transgenic mice for inducible gene overexpression in pancreatic cells define glucocorticoid receptor-mediated regulations of beta cells. PLoS One e30210


Boghaert, Eline Gjorevski, Nikolce Gleghorn, Jason P. Lee, KangAe Nelson, Celeste M. Radisky, Derek C. (2012) Host epithelial geometry regulates breast cancer cell invasiveness. Proceedings of the National Academy of Sciences 19632-19637


Bai, Yan Bonilla-Claudio, Margarita Klysik, Elzbieta Martin, James F. Selever, Jennifer Wang, Jun (2012) Bmp signaling regulates a dose-dependent transcriptional program to control facial skeletal development. Development 709-719


Bouquet, C. Melchers, F. (2012) Pim1 and Myc reversibly transform murine precursor B lymphocytes but not mature B lymphocytes. Eur J Immunol 522-32


Bradbury, Peta Mahmassani, Maha O'Neill, Geraldine M. Paul, Andre Turner, Kylie Verrills, Nicole M. Zhong, Jessie (2012) PP2A phosphatase suppresses function of the mesenchymal invasion regulator NEDD9. Biochimica et Biophysica Acta (BBA) - Molecular Cell Research 290-297


Braten, O. Ciechanover, A. Kravtsova-Ivantsiv, Y. Shabek, N. (2012) Generation of free ubiquitin chains is up-regulated in stress and facilitated by the HECT domain ubiquitin ligases UFD4 and HUL5. Biochem J 611-7


Brauer, H. Horstmann, M. Jucker, M. Muller-Tidow, C. Strauss, J. Wegner, W. (2012) Leukemia-associated mutations in SHIP1 inhibit its enzymatic activity, interaction with the GM-CSF receptor and Grb2, and its ability to inactivate PI3K/AKT signaling. Cell Signal 2095-101


Briand, Olivier Carpentier, Rodolphe Eeckhoute, Jerome Gmyr, Valery Helleboid-Chapman, Audrey Hennuyer, Nathalie Kerr-Conte, Julie Lefebvre, Philippe Moerman, Ericka Pattou, Francois Ploton, Maheul Staels, Bart Vandewalle, Brigitte (2012) The Nuclear Orphan Receptor Nur77 Is a Lipotoxicity Sensor Regulating Glucose-Induced Insulin Secretion in Pancreatic {beta}-Cells. Mol. Endocrinol. 399-413


Bridges, James P. Ikegami, Machiko Lin, Sui Shannon, John M. (2012) Conditional hypoxia inducible factor-1?± induction in embryonic pulmonary epithelium impairs maturation and augments lymphangiogenesis. Developmental Biology 24-41


Aaronson, Stuart A. Brown-Endres, Lauren Kim, Hyung-Gu Lee, Sam W. Mandinova, Anna Mu?±oz-Fontela, C?©sar Namba, Takushi Schoenfeld, David Tian, Fang (2012) Expression of the p53 Target CDIP Correlates with Sensitivity to TNF?±-Induced Apoptosis in Cancer Cells. Cancer Research 2373-2382


Aifantis, Iannis Apostolou, Effie Aranda-Orgilles, Beatriz Buckley, Shannon¬?M Chen, Emily¬?I Dasgupta, Ramanuj Farnsworth, Charles¬?L Hochedlinger, Konrad Koller, Antonius¬?A Loizou, Evangelia Moran-Crusio, Kelly Silva, Jeffrey¬?C Stadtfeld, Matthias Strikoudis, Alexandros (2012) Regulation of Pluripotency and Cellular Reprogramming by the Ubiquitin-Proteasome System. Cell Stem Cell 783-798


Buganim, Yosef Cheng, Albert¬?W Faddah, Dina¬?A Ganz, Kibibi Itskovich, Elena Jaenisch, Rudolf Klemm, Sandy¬?L Markoulaki, Styliani van¬?Oudenaarden, Alexander (2012) Single-Cell Expression Analyses during Cellular Reprogramming Reveal an Early Stochastic and a Late Hierarchic Phase. Cell 1209-1222


Buganim, Yosef Cheng, Albert¬?W Fu, Dongdong Ganz, Kibibi Hu, Yueh-Chiang Itskovich, Elena Jaenisch, Rudolf Page, David¬?C Sarkar, Sovan Welstead, G. Grant (2012) Direct Reprogramming of Fibroblasts into Embryonic Sertoli-like Cells by Defined Factors. Cell Stem Cell 373-386


Bowyer, P. Buied, A. Denning, D. W. Moore, C. B. (2012) High-level expression of cyp51B in azole-resistant clinical Aspergillus fumigatus isolates. J. Antimicrob. Chemother. dks451


Archer, Trevor K. Burd, Craig J. Crusselle-Davis, Valerie J. Kissling, Grace E. Phadke, Dhiral Shah, Ruchir R. Ward, James M. (2012) Analysis of Chromatin Dynamics during Glucocorticoid Receptor Activation. Molecular and Cellular Biology 1805-1817


Byg, L. M. Clausen, D. Forslund, O. Norrild, B. Vasiljevic, N. Vidlund, J. (2012) NF-kappaB signalling is attenuated by the E7 protein from cutaneous human papillomaviruses. Virus Res 48-53


Bodega, Beatrice Cabianca, Daphne¬?S Casa, Valentina Gabellini, Davide Ginelli, Enrico Tanaka, Yujiro Xynos, Alexandros (2012) A Long ncRNA Links Copy Number Variation to a Polycomb/Trithorax Epigenetic Switch in FSHD Muscular Dystrophy. Cell 819-831


Bachellier-Bassi, S. Cabral, V. Chaudhari, Y. Chauvel, M. d'Enfert, C. Firon, A. Legrand, M. Munro, C. A. Nesseir, A. (2012) Modular gene over-expression strategies for Candida albicans. Methods Mol Biol 227-44


B?ºttner, Bettina Cadenas, Cristina Franckenstein, Dennis Hammad, Seddik Hayen, Heiko Hein, Eva-Maria Hellwig, Birte Hengstler, Jan G. Hermes, Matthias Langer, Alice Marchan, Rosemarie Peksel, Beg?ºm Rahnenf?ºhrer, J??rg Selinski, Silvia T??r??k, Zsolt V??gh, L?°szl?? Vosbeck, Sonja (2012) Glycerophospholipid profile in oncogene-induced senescence. Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids 1256-1268


Aldrich, Carol E. Block, Timothy M. Cai, Dawei Cuconati, Andrea Guo, Haitao Guo, Ju-Tao Mason, William S. Mills, Courtney Saputelli, Jeffry R. Xu, Xiaodong Yan, Ran Yu, Wenquan (2012) Identification of Disubstituted Sulfonamide Compounds as Specific Inhibitors of Hepatitis B Virus Covalently Closed Circular DNA Formation. Antimicrob. Agents Chemother. 4277-4288


Albring, J??rn C. Cai, Mi Gill, Jennifer G. KC, Wumesh Langer, Ellen M. Murphy, Kenneth M. Murphy, Theresa L. Satpathy, Ansuman T. (2012) Dual actions of Meis1 inhibit erythroid progenitor development and sustain general hematopoietic cell proliferation. Blood 335-346


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Crow, M. S. Healey, M. Molina, C. A. (2012) Ras-induced melanoma transformation is associated with the proteasomal degradation of the transcriptional repressor ICER. Mol Carcinog


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Anderson, K. M. Bastola, D. Bies, J. Chan, W. C. Christman, J. K. Felsher, D. W. Greiner, T. C. Hannah, J. Hlady, R. A. Iqbal, J. Joshi, S. Klinkebiel, D. Lockridge, O. Novakova, S. Opavska, J. Opavsky, R. Peters, S. L. Siebler, H. M. Simpson, M. A. Smith, L. M. Wagner, K. U. (2012) Loss of Dnmt3b function upregulates the tumor modifier Ment and accelerates mouse lymphomagenesis. J Clin Invest 163-77


Bilban, Martin Blatt, Katharina Cerny-Reiterer, Sabine Gisslinger, Bettina Gisslinger, Heinz Herrmann, Harald Hoermann, Gregor Kralovics, Robert Mannhalter, Christine Mayerhofer, Matthias Mullauer, Leonhard Valent, Peter (2012) Identification of oncostatin M as a JAK2 V617F-dependent amplifier of cytokine production and bone marrow remodeling in myeloproliferative neoplasms. FASEB J 894-906


Hoffmann, Anke Spengler, Dietmar (2012) Transient Neonatal Diabetes Mellitus Gene Zac1 Impairs Insulin Secretion in Mice through Rasgrf1. Molecular and Cellular Biology 2549-2560


Banning, C. Brenner, M. Hauber, J. Hoffmann, D. Krepstakies, M. Mariyanna, L. Millar, D. P. Schindler, M. Schwarck, D. (2012) Formation of trans-activation competent HIV-1 Rev:RRE complexes requires the recruitment of multiple protein activation domains. PLoS One e38305


Backstrom, Erica Bry, Kristina Bry, Maija Hogmalm, Anna Lappalainen, Urpo Lukkarinen, Heikki P. (2012) Role of CXC Chemokine Receptor-2 in a Murine Model of Bronchopulmonary Dysplasia. Am. J. Respir. Cell Mol. Biol. 746-758


Hoijman, E. Joffe, E. B. Kalko, S. G. Kordon, E. C. Morales-Ruiz, M. Pecci, A. Rocha-Viegas, L. Rubinstein, N. (2012) Glucocorticoid alternative effects on proliferating and differentiated mammary epithelium are associated to opposite regulation of cell-cycle inhibitor expression. J Cell Physiol 1721-30


Bauer, Manuel Cleveland, Don W. Fachinetti, Daniele Holland, Andrew J. Nigg, Erich A. Verma, Inder M. Zhu, Quan (2012) The autoregulated instability of Polo-like kinase 4 limits centrosome duplication to once per cell cycle. Genes & Development 2684-2689


Behr, Barry Dutta, Debasree Gallagher, Patrick G. Golos, Thaddeus G. Gunewardena, Sumedha Home, Pratik Larson, Melissa Pal, Arindam Paul, Soumen Petroff, Margaret Ray, Soma Saha, Biswarup Schulz, Vincent P. Vivian, Jay L. White, Kenneth L. Yoo, Byunggil (2012) Altered subcellular localization of transcription factor TEAD4 regulates first mammalian cell lineage commitment. Proceedings of the National Academy of Sciences 7362-7367


Blesch, Armin Hou, Shaoping Motsch, Melanie Nicholson, LaShae van Niekerk, Erna (2012) Dependence of Regenerated Sensory Axons on Continuous Neurotrophin-3 Delivery. The Journal of Neuroscience 13206-13220


Chang, H. T. Hsieh, C. H. Liu, R. S. Shen, W. C. Shyu, W. C. (2012) Imaging the impact of Nox4 in cycling hypoxia-mediated U87 glioblastoma invasion and infiltration. Mol Imaging Biol 489-99


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Chang, Tsu-Chung Chu, Chin-Chen Hsu, Tzu-Hui Hung, May-Whey Jiang, Shun-Yuan Lin, Huai-En Ni, Wen-Chieh (2012) Expression of the class II tumor suppressor gene RIG1 is directly regulated by p53 tumor suppressor in cancer cell lines. FEBS Letters 1287-1293


Chang, Wen-Chang Chen, Szu-Yu Hsu, Tsung-I. Huang, Shih-Ting Hung, Jan-Jong Su, Wu-Chou Wang, Mei-Chun Yeh, Yu-Min (2012) Betulinic Acid Decreases Specificity Protein 1 (Sp1) Level via Increasing the Sumoylation of Sp1 to Inhibit Lung Cancer Growth. Mol. Pharmacol. 1115-1128


Agudelo-Garcia, Paula A. Cole, Susan E. Dolan, Claire E. Hu, Bin Mora, Maria E. Nandhu, Mohan S. Nuovo, Gerard J. Saldivar, Joshua C. Sim, Hosung Viapiano, Mariano S. (2012) Fibulin-3 Promotes Glioma Growth and Resistance through a Novel Paracrine Regulation of Notch Signaling. Cancer Research 3873-3885


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Bi, F. Huang, C. Tong, J. Xia, X. G. Zhou, H. (2012) Mutant TDP-43 in motor neurons promotes the onset and progression of ALS in rats. J Clin Invest 107-18


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Driegen, Siska Grosveld, Frank Gunther, Andreas Huang, Yadi Kempen, Marjon Buscop-van Mahavadi, Poornima Meijer, Dies Munck, Anne Boerema-de Rottier, Robbert J. Swagemakers, Sigrid Tibboel, Dick van der Spek, Peter van Ijcken, Wilfred (2012) Hypoxia-Inducible Factor 2{alpha} Plays a Critical Role in the Formation of Alveoli and Surfactant. Am. J. Respir. Cell Mol. Biol. 224-232


Huang, Yali Osorno, Rodrigo Tsakiridis, Anestis Wilson, Valerie (2012) In¬?Vivo Differentiation Potential of Epiblast Stem Cells Revealed by Chimeric Embryo Formation. Cell Reports 1571-1578


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Bader, Oliver Gross, Uwe Hull, Claire M. Kelly, Diane E. Kelly, Steven L. Parker, Josie E. Warrilow, Andrew G. S. Weig, Michael (2012) Facultative Sterol Uptake in an Ergosterol-Deficient Clinical Isolate of Candida glabrata Harboring a Missense Mutation in ERG11 and Exhibiting Cross-Resistance to Azoles and Amphotericin B. Antimicrob. Agents Chemother. 4223-4232


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Ebnet, Klaus Gerke, Volker Iden, Sandra Misselwitz, Steve Peddibhotla, Swetha S.D. Rehder, Daniela Robenek, Horst Suzuki, Atsushi Tuncay, Huseyin (2012) aPKC phosphorylates JAM-A at Ser285 to promote cell contact maturation and tight junction formation. J. Cell Biol. 623-639


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Chao, Ti-Chun Jeng, King-Song Lai, Chao-Kuen Lai, Michael M. C. Saxena, Vikas (2012) Annexin A2 Is Involved in the Formation of Hepatitis C Virus Replication Complex on the Lipid Raft. Journal of Virology 4139-4150


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Arzumanyan, Alla Bassit, Leda Clayton, Marcia M. Feitelson, Mark A. Kohler, James J. Obikhod, Aleksandr Schinazi, Raymond F. Sun, Bill (2012) Evaluation of Single and Combination Therapies with Tenofovir Disoproxil Fumarate and Emtricitabine In Vitro and in a Robust Mouse Model Supporting High Levels of Hepatitis B Virus Replication. Antimicrobial Agents and Chemotherapy 6186-6191


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Gupta, I. Jensen, T. H. Moore, C. Olszewski, P. Pelechano, V. Poulsen, M. B. Saguez, C. Schmid, M. Steinmetz, L. M. (2012) Rrp6p controls mRNA poly(A) tail length and its decoration with poly(A) binding proteins. Mol Cell 267-80


Eriksson, Maria Koskela, Antti Nilsson, Ola Ohlsson, Claes Rozell, Bj??rn Schmidt, Eva Tuukkanen, Juha (2012) Expression of the Hutchinson-Gilford Progeria Mutation during Osteoblast Development Results in Loss of Osteocytes, Irregular Mineralization, and Poor Biomechanical Properties. Journal of Biological Chemistry 33512-33522


Baum, K. Lao, A. Nykjaer, A. Petersen, C. M. Rateitschak, K. Schmidt, V. Schmitz, Y. Teichmann, A. Wiesner, B. Willnow, T. E. Wolf, J. Wolkenhauer, O. (2012) Quantitative modelling of amyloidogenic processing and its influence by SORLA in Alzheimer\'s disease. EMBO J 187-200


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Condorelli, Gianluigi Maejima, Yasuhiro Robbins, Jeffrey Sadoshima, Junichi Sciarretta, Sebastiano Shao, Dan Volpe, Massimo Zhai, Peiyong (2012) Rheb is a Critical Regulator of Autophagy During Myocardial Ischemia / Clinical Perspective. Circulation 1134-1146


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Emery, Amanda Everly, David N. Holthusen, Kirsten Talaty, Pooja (2012) Identification of Transmembrane Protein 134 as a Novel LMP1-Binding Protein by Using Bimolecular Fluorescence Complementation and an Enhanced Retroviral Mutagen. Journal of Virology 11345-11355


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