Leadership In Controlled Gene Expression

1996

Adachi, J., Ookawa, K., Shiseki, M., Okazaki, T., Tsuchida, S., Morishita, K., and Yokota, J. (1996). Induction of apoptosis but not G1 arrest by expression of the wild-type p53 gene in small cell lung carcinoma. Cell Growth Differ 7, 879-886.

 

Ahn, K., Meyer, T. H., Uebel, S., Sempe, P., Djaballah, H., Yang, Y., Peterson, P. A., Fruh, K., and Tampe, R. (1996). Molecular mechanism and species specificity of TAP inhibition by herpes simplex virus ICP47. Embo J 15, 3247-3255.

 

Anderson, M. T., Tjioe, I. M., Lorincz, M. C., Parks, D. R., Herzenberg, L. A., Nolan, G. P., and Herzenberg, L. A. (1996). Simultaneous fluorescence-activated cell sorter analysis of two distinct transcriptional elements within a single cell using engineered green fluorescent proteins. Proc Natl Acad Sci U S A 93, 8508-8511.

 

Baasner, S., von Melchner, H., Klenner, T., Hilgard, P., and Beckers, T. (1996). Reversible tumorigenesis in mice by conditional expression of the HER2/c-erbB2 receptor tyrosine kinase. Oncogene 13, 901-911.

 

Bargou, R. C., Wagener, C., Bommert, K., Arnold, W., Daniel, P. T., Mapara, M. Y., Grinstein, E., Royer, H. D., and Dorken, B. (1996). Blocking the transcription factor E2F/DP by dominant-negative mutants in a normal breast epithelial cell line efficiently inhibits apoptosis and induces tumor growth in SCID mice. J Exp Med 183, 1205-1213.

 

Bargou, R. C., Wagener, C., Bommert, K., Mapara, M. Y., Daniel, P. T., Arnold, W., Dietel, M., Guski, H., Feller, A., Royer, H. D., and Dorken, B. (1996). Overexpression of the death-promoting gene bax-alpha which is downregulated in breast cancer restores sensitivity to different apoptotic stimuli and reduces tumor growth in SCID mice [see comments]. J Clin Invest 97, 2651-2659.

 

Beauparlant, P., Lin, R., and Hiscott, J. (1996). The role of the C-terminal domain of I kappa B alpha in protein degradation and stabilization. J Biol Chem 271, 10690-10696.

 

Benedict, C. M., and Clawson, G. A. (1996). Nuclear multicatalytic proteinase subunit RRC3 is important for growth regulation in hepatocytes. Biochemistry 35, 11612-11621.

 

Bertran, J., Miller, J. L., Yang, Y., Fenimore-Justman, A., Rueda, F., Vanin, E. F., and Nienhuis, A. W. (1996). Recombinant adeno-associated virus-mediated high-efficiency, transient expression of the murine cationic amino acid transporter (ecotropic retroviral receptor) permits stable transduction of human HeLa cells by ecotropic retroviral vectors. J Virol 70, 6759-6766.

 

Bunker, C. A., and Kingston, R. E. (1996). Activation domain-mediated enhancement of activator binding to chromatin in mammalian cells. Proc Natl Acad Sci U S A 93, 10820-10825.

 

Cao, J., Park, I. W., Cooper, A., and Sodroski, J. (1996). Molecular determinants of acute single-cell lysis by human immunodeficiency virus type 1. J Virol 70, 1340-1354.

 

Cayrol, C., and Flemington, E. K. (1996). The Epstein-Barr virus bZIP transcription factor Zta causes G0/G1 cell cycle arrest through induction of cyclin-dependent kinase inhibitors. Embo J 15, 2748-2759.

 

Chen, X., Ko, L. J., Jayaraman, L., and Prives, C. (1996). p53 levels, functional domains, and DNA damage determine the extent of the apoptotic response of tumor cells. Genes Dev 10, 2438-2451.

 

Chen, S. T., Iida, A., Guo, L., Friedmann, T., and Yee, J. K. (1996). Generation of packaging cell lines for pseudotyped retroviral vectors of the G protein of vesicular stomatitis virus by using a modified tetracycline inducible system. Proc Natl Acad Sci U S A 93, 10057-10062.

 

Chrast-Balz, J., and Hooft van Huijsduijnen, R. (1996). Bi-directional gene switching with the tetracycline repressor and a novel tetracycline antagonist. Nucleic Acids Res 24, 2900-2904.

 

Corti, O., Horellou, P., Colin, P., Cattaneo, E., and Mallet, J. (1996). Intracerebral tetracycline-dependent regulation of gene expression in grafts of neural precursors. Neuroreport 7, 1655-1659.

 

Dutartre, H., Davoust, J., Gorvel, J. P., and Chavrier, P. (1996). Cytokinesis arrest and redistribution of actin-cytoskeleton regulatory components in cells expressing the Rho GTPase CDC42Hs. J Cell Sci 109, 367-377.

 

Ewald, D., Li, M., Efrat, S., Auer, G., Wall, R. J., Furth, P. A., and Hennighausen, L. (1996). Time-sensitive reversal of hyperplasia in transgenic mice expressing SV40 T antigen. Science 273, 1384-1386.

 

Faris, M., Kokot, N., Lee, L., and Nel, A. E. (1996). Regulation of interleukin-2 transcription by inducible stable expression of dominant negative and dominant active mitogen-activated protein kinase kinase kinase in jurkat T cells. Evidence for the importance of Ras in a pathway that is controlled by dual receptor stimulation. J Biol Chem 271, 27366-27373.

 

Flanagan, W. M., Kothavale, A., and Wagner, R. W. (1996). Effects of oligonucleotide length, mismatches and mRNA levels on C-5 propyne-modified antisense potency. Nucleic Acids Res 24, 2936-2941.

 

Floettmann, J. E., Ward, K., Rickinson, A. B., and Rowe, M. (1996). Cytostatic effect of Epstein-Barr virus latent membrane protein-1 analyzed using tetracycline-regulated expression in B cell lines. Virology 223, 29-40.

 

Fornerod, M., Boer, J., van Baal, S., Morreau, H., and Grosveld, G. (1996). Interaction of cellular proteins with the leukemia specific fusion proteins DEK-CAN and SET-CAN and their normal counterpart, the nucleoporin CAN. Oncogene 13, 1801-1808.

 

Galaktionov, K., Chen, X., and Beach, D. (1996). Cdc25 cell-cycle phosphatase as a target of c-myc. Nature 382, 511-517.

 

Gil, P., and Green, P. J. (1996). Multiple regions of the Arabidopsis SAUR-AC1 gene control transcript abundance: the 3' untranslated region functions as an mRNA instability determinant. Embo J 15, 1678-1686.

 

Haber, D. A., Englert, C., and Maheswaran, S. (1996). Functional properties of WT1. Med Pediatr Oncol 27, 453-455.

 

Ho, D. Y., McLaughlin, J. R., and Sapolsky, R. M. (1996). Inducible gene expression from defective herpes simplex virus vectors using the tetracycline-responsive promoter system. Brain Res Mol Brain Res 41, 200-209.

 

Hofmann, A., Nolan, G. P., and Blau, H. M. (1996). Rapid retroviral delivery of tetracycline-inducible genes in a single autoregulatory cassette [see comments]. Proc Natl Acad Sci U S A 93, 5185-5190.

 

Hoshimaru, M., Ray, J., Sah, D. W., and Gage, F. H. (1996). Differentiation of the immortalized adult neuronal progenitor cell line HC2S2 into neurons by regulatable suppression of the v-myc oncogene. Proc Natl Acad Sci U S A 93, 1518-1523.

 

Hwang, J. J., Scuric, Z., and Anderson, W. F. (1996). Novel Retroviral Vector Transferring a Suicide Gene and a Selectable Marker Gene With Enhanced Gene Expression By Using a Tetracycline-Responsive Expression System. Journal Of Virology 70, 8138-8141.

 

Iacampo, S., and Cochrane, A. (1996). Human immunodeficiency virus type 1 Rev function requires continued synthesis of its target mRNA. J Virol 70, 8332-8339.

 

Iida, A., Chen, S. T., Friedmann, T., and Yee, J. K. (1996). Inducible gene expression by retrovirus-mediated transfer of a modified tetracycline-regulated system. J Virol 70, 6054-6059.

 

Jin, P., Gu, Y., and Morgan, D. O. (1996). Role of inhibitory CDC2 phosphorylation in radiation-induced G2 arrest in human cells. J Cell Biol 134, 963-970.

 

Kessler, O., and Chasin, L. A. (1996). Effects of nonsense mutations on nuclear and cytoplasmic adenine phosphoribosyltransferase RNA. Mol Cell Biol 16, 4426-4435.

 

Kistner, A., Gossen, M., Zimmermann, F., Jerecic, J., Ullmer, C., Lubbert, H., and Bujard, H. (1996). Doxycycline-mediated quantitative and tissue-specific control of gene expression in transgenic mice. Proc Natl Acad Sci U S A 93, 10933-10938.

 

Kitamura, M. (1996). Creation of a reversible on/off system for site-specific in vivo control of exogenous gene activity in the renal glomerulus. Proc Natl Acad Sci U S A 93, 7387-7391.

 

Knaus, P. I., Lindemann, D., DeCoteau, J. F., Perlman, R., Yankelev, H., Hille, M., Kadin, M. E., and Lodish, H. F. (1996). A dominant inhibitory mutant of the type II transforming growth factor beta receptor in the malignant progression of a cutaneous T-cell lymphoma. Mol Cell Biol 16, 3480-3489.

 

Langer, S. J., and Schaack, J. (1996). 293 cell lines that inducibly express high levels of adenovirus type 5 precursor terminal protein. Virology 221, 172-179.

 

Lassus, P., Ferlin, M., Piette, J., and Hibner, U. (1996). Anti-apoptotic activity of low levels of wild-type p53. Embo J 15, 4566-4573.

 

Lauffenburger, D. A., Chu, L. L., French, A., Oehrtman, G., Reddy, C., Wells, A., Niyogi, S., and Wiley, H. S. (1996). Engineering Dynamics Of Growth Factors and Other Therapeutic Ligands. Biotechnology and Bioengineering 52, 61-80.

 

Lewis, J. G., Lin, K. Y., Kothavale, A., Flanagan, W. M., Matteucci, M. D., DePrince, R. B., Mook, R. A., Jr., Hendren, R. W., and Wagner, R. W. (1996). A serum-resistant cytofectin for cellular delivery of antisense oligodeoxynucleotides and plasmid DNA. Proc Natl Acad Sci U S A 93, 3176-3181.

 

Liaudet-Coopman, E. D., Schulte, A. M., Cardillo, M., and Wellstein, A. (1996). A tetracycline-responsive promoter system reveals the role of a secreted binding protein for FGFs during the early phase of tumor growth. Biochem Biophys Res Commun 229, 930-937.

 

Lin, R., Beauparlant, P., Makris, C., Meloche, S., and Hiscott, J. (1996). Phosphorylation of IkappaBalpha in the C-terminal PEST domain by casein kinase II affects intrinsic protein stability. Mol Cell Biol 16, 1401-1409.

 

Lukas, J., Petersen, B. O., Holm, K., Bartek, J., and Helin, K. (1996). Deregulated expression of E2F family members induces S-phase entry and overcomes p16INK4A-mediated growth suppression. Mol Cell Biol 16, 1047-1057.

 

Lutz, W., Stohr, M., Schurmann, J., Wenzel, A., Lohr, A., and Schwab, M. (1996). Conditional expression of N-myc in human neuroblastoma cells increases expression of alpha-prothymosin and ornithine decarboxylase and accelerates progression into S-phase early after mitogenic stimulation of quiescent cells. Oncogene 13, 803-812.

 

Maxwell, I. H., Spitzer, A. L., Long, C. J., and Maxwell, F. (1996). Autonomous parvovirus transduction of a gene under control of tissue-specific or inducible promoters. Gene Ther 3, 28-36.

 

Mayford, M., Bach, M. E., Huang, Y. Y., Wang, L., Hawkins, R. D., and Kandel, E. R. (1996). Control of memory formation through regulated expression of a CaMKII transgene. Science 274, 1678-1683.

 

Moradpour, D., Englert, C., Wakita, T., and Wands, J. R. (1996). Characterization of cell lines allowing tightly regulated expression of hepatitis C virus core protein. Virology 222, 51-63.

 

Neering, S. J., Hardy, S. F., Minamoto, D., Spratt, S. K., and Jordan, C. T. (1996). Transduction of primitive human hematopoietic cells with recombinant adenovirus vectors. Blood 88, 1147-1155.

 

Orimoto, K., Tsuchiya, H., Kobayashi, T., Matsuda, T., and Hino, O. (1996). Suppression of the neoplastic phenotype by replacement of the Tsc2 gene in Eker rat renal carcinoma cells. Biochem Biophys Res Commun 219, 70-75.

 

Ory, D. S., Neugeboren, B. A., and Mulligan, R. C. (1996). A stable human-derived packaging cell line for production of high titer retrovirus/vesicular stomatitis virus G pseudotypes. Proc Natl Acad Sci U S A 93, 11400-11406.

 

Paulus, W., Baur, I., Boyce, F. M., Breakefield, X. O., and Reeves, S. A. (1996). Self-contained, tetracycline-regulated retroviral vector system for gene delivery to mammalian cells. J Virol 70, 62-67.

 

Paulus, W., Baur, I., Beutler, A. S., and Reeves, S. A. (1996). Diffuse brain invasion of glioma cells requires beta 1 integrins. Lab Invest 75, 819-826.

 

Schultze, N., Burki, Y., Lang, Y., Certa, U., and Bluethmann, H. (1996). Efficient control of gene expression by single step integration of the tetracycline system in transgenic mice [In Process Citation]. Nat Biotechnol 14, 499-503.

 

Shan, B., Farmer, A. A., and Lee, W. H. (1996). The molecular basis of E2F-1/DP-1-induced S-phase entry and apoptosis. Cell Growth Differ 7, 689-697.

 

Shockett, P. E., and Schatz, D. G. (1996). Diverse strategies for tetracycline-regulated inducible gene expression [see comments]. Proc Natl Acad Sci U S A 93, 5173-5176.

 

Shulze, A., Zerfass-Thome, K., Berges, J., Middendorp, S., Jansen-Durr, P., and Henglein, B. (1996). Anchorage-dependent transcription of the cyclin A gene. Mol Cell Biol 16, 4632-4638.

 

Sofer-Levi, Y., and Resnitzky, D. (1996). Apoptosis induced by ectopic expression of cyclin D1 but not cyclin E. Oncogene 13, 2431-2437.

 

Speed, C. J., Little, P. J., Hayman, J. A., and Mitchell, C. A. (1996). Underexpression of the 43 kDa inositol polyphosphate 5-phosphatase is associated with cellular transformation. Embo J 15, 4852-4861.

 

St-Onge, L., Furth, P. A., and Gruss, P. (1996). Temporal control of the Cre recombinase in transgenic mice by a tetracycline responsive promoter. Nucleic Acids Res 24, 3875-3877.

 

Theroux, T. L., Esbenshade, T. A., Peavy, R. D., and Minneman, K. P. (1996). Coupling efficiencies of human alpha 1-adrenergic receptor subtypes: titration of receptor density and responsiveness with inducible and repressible expression vectors. Mol Pharmacol 50, 1376-1387.

 

Vieira, A. V., Lamaze, C., and Schmid, S. L. (1996). Control of EGF receptor signaling by clathrin-mediated endocytosis. Science 274, 2086-2089.

 

Vignali, D. A., Carson, R. T., Chang, B., Mittler, R. S., and Strominger, J. L. (1996). The two membrane proximal domains of CD4 interact with the T cell receptor. J Exp Med 183, 2097-2107.

 

Wagener, C., Bargou, R. C., Daniel, P. T., Bommert, K., Mapara, M. Y., Royer, H. D., and Dorken, B. (1996). Induction of the death-promoting gene bax-alpha sensitizes cultured breast-cancer cells to drug-induced apoptosis. Int J Cancer 67, 138-141.

 

Wang, J., Han, W., Zborowska, E., Liang, J., Wang, X., Willson, J. K. V., Sun, L., and Brattain, M. G. (1996). Reduced expression of transforming growth factor beta type I receptor contributes to the malignancy of human colon carcinoma cells. J Biol Chem 271, 17366-17371.

 

Wang, J., Takagaki, Y., and Manley, J. L. (1996). Targeted disruption of an essential vertebrate gene: ASF/SF2 is required for cell viability. Genes Dev 10, 2588-2599.

 

Wang, K., Yin, X. M., Chao, D. T., Milliman, C. L., and Korsmeyer, S. J. (1996). BID: a novel BH3 domain-only death agonist. Genes Dev 10, 2859-2869.

 

Wu, Z., Bucher, N. L., and Farmer, S. R. (1996). Induction of peroxisome proliferator-activated receptor gamma during the conversion of 3T3 fibroblasts into adipocytes is mediated by C/EBPbeta, C/EBPdelta, and glucocorticoids. Mol Cell Biol 16, 4128-4136.

 

Wu, S. Y., and Chiang, C. M. (1996). Establishment of stable cell lines expressing potentially toxic proteins by tetracycline-regulated and epitope-tagging methods. Biotechniques 21, 718-722, 724-715.

 

Xiang, J., Chao, D. T., and Korsmeyer, S. J. (1996). BAX-induced cell death may not require interleukin 1 beta-converting enzyme-like proteases. Proc Natl Acad Sci U S A 93, 14559-14563.

 

Yin, D. X., and Schimke, R. T. (1996). Inhibition of apoptosis by overexpressing Bcl-2 enhances gene amplification by a mechanism independent of aphidicolin pretreatment. Proc Natl Acad Sci U S A 93, 3394-3398.

 

Yin, D. X., Zhu, L., and Schimke, R. T. (1996). Tetracycline-controlled gene expression system achieves high-level and quantitative control of gene expression. Anal Biochem 235, 195-201.

 

Yu, H., Rabson, A. B., Kaul, M., Ron, Y., and Dougherty, J. P. (1996). Inducible human immunodeficiency virus type 1 packaging cell lines. J Virol 70, 4530-4537.

 

Yu, J. S., Sena-Esteves, M., Paulus, W., Breakefield, X. O., and Reeves, S. A. (1996). Retroviral delivery and tetracycline-dependent expression of IL-1beta-converting enzyme (ICE) in a rat glioma model provides controlled induction of apoptotic death in tumor cells. Cancer Res 56, 5423-5427.

 

Yu, Z., Redfern, C. S., and Fishman, G. I. (1996). Conditional transgene expression in the heart. Circ Res 79, 691-697.

 

Yue, Z., and Shatkin, A. J. (1996). Regulated, stable expression and nuclear presence of retrovirus double-stranded RNA-binding protein sigma3 in HeLa cells. J Virol 70, 3497-3501.

 

Zeidler, M., Gatz, C., Hartmann, E., and Hughes, J. (1996). Tetracycline-regulated reporter gene expression in the moss Physcomitrella patens. Plant Mol Biol 30, 199-205.

 

Zhang, Q. X., Davis, I. D., and Baldwin, G. S. (1996). Controlled overexpression of selected domains of the P85 subunit of phosphatidylinositol 3-kinase reverts v-Ha-Ras transformation. Biochim Biophys Acta 1312, 207-214.

 

Zwijsen, R. M., Klompmaker, R., Wientjens, E. B., Kristel, P. M., van der Burg, B., and Michalides, R. J. (1996). Cyclin D1 triggers autonomous growth of breast cancer cells by governing cell cycle exit. Mol Cell Biol 16, 2554-2560.