Leadership In Controlled Gene Expression

2017

Belur, N. R. Dzaferbegovic, H. Fredriksen, K. Gelyana, E. Jeon, S. Mazzulli, J. R. Moise, A. C. Stojkovska, I. Toker, N. J. Zunke, F. (2017) Reversible Conformational Conversion of alpha-Synuclein into Toxic Assemblies by Glucosylceramide. Neuron

 

Bork, T. Burtin, M. Cohen, C. D. Eulenbruch, K. Gerber, S. Godel, M. Hartleben, B. Herbach, N. Huber, T. B. Kretz, O. Liang, W. Munder, S. Rastaldi, M. P. Reiser, J. Simons, M. Terzi, F. Tharaux, P. L. Viau, A. Walz, G. Wanner, N. Wei, C. Zschiedrich, S. (2017) Targeting mTOR Signaling Can Prevent the Progression of FSGS. J Am Soc Nephrol 2144-2157

 

Lan, K. Liang, D. Ma, C. Meng, Z. Sun, R. Zou, Z. (2017) Guanylate-Binding Protein 1 Inhibits Nuclear Delivery of Kaposi\'s Sarcoma-Associated Herpesvirus Virions by Disrupting Formation of Actin Filament. J Virol

 

Commins, R. M. T. Dirksen, U. Erkizan, H. V. Graham, G. T. Haladyna, J. N. Hogarty, M. D. Hong, S. H. Moseley, E. Parks, S. Selvanathan, S. P. Toretsky, J. A. Uren, A. Zollner, S. K. (2017) Inhibition of the oncogenic fusion protein EWS-FLI1 causes G2-M cell cycle arrest and enhanced vincristine sensitivity in Ewing\'s sarcoma. Sci Signal

 

Ahmari, Susanne E. Bubser, Michael Chohan, Muhammad O. Flicker, Daniel Jones, Carrie K. Kellendonk, Christoph Kopelman, Jared M. Krasnow, Emily N. Moore, Holly Nautiyal, Katherine M. Stanwood, Gregg Tanaka, Kenji Fransis Veenstra-VanderWeele, Jeremy Zike, Isaac D. (2017) OCD candidate gene SLC1A1/EAAT3 impacts basal ganglia-mediated activity and stereotypic behavior. Proceedings of the National Academy of Sciences 5719-5724

 

Gesenhues, F. Hinkel, R. Husada, W. Jiang, Q. Kraus, M. Kupatt, C. Laugwitz, K. L. le Noble, F. Pinkenburg, O. Trenkwalder, T. Weber, C. Ziegler, T. (2017) Steerable Induction of the Thymosin beta4/MRTF-A Pathway via AAV-Based Overexpression Induces Therapeutic Neovascularization. Hum Gene Ther

 

Trueb, B. Zhuang, L. (2017) Evolution of the fusogenic activity of the receptor FGFRL1. Arch Biochem Biophys 54-64

 

Cao, H. Deng, Y. Ghaben, A. L. Gordillo, R. Gupta, R. K. Li, Y. Lin, H. V. Scherer, P. E. Scott, D. A. Shao, M. Xing, C. Xu, P. Zagnitko, O. Zhang, B. B. Zhang, F. Zhao, S. Zhu, Y. (2017) Hepatic GALE Regulates Whole-Body Glucose Homeostasis by Modulating Tff3 Expression. Diabetes 2789-2799

 

Cao, H. Dong, Z. Guo, F. He, S. Hou, X. Khan, A. Li, H. Look, A. T. Lopez, G. Lummertz da Rocha, E. Maris, J. M. McNiven, M. A. Meves, A. Neuberg, D. S. Oldridge, D. Perez-Atayde, A. R. Salazar, B. M. Tao, T. Ung, C. Y. van Deursen, J. M. van Ree, J. H. Weichert-Leahey, N. Weroha, S. J. Wood, A. C. Zhang, C. Zhang, X. Zhu, S. Zimmerman, M. W. (2017) LMO1 Synergizes with MYCN to Promote Neuroblastoma Initiation and Metastasis. Cancer Cell 310-323 e5

 

Akagi, T. Horike, S. I. Song, X. Ueda, A. Yokota, T. Zhu, B. (2017) Baf53a is involved in survival of mouse ES cells, which can be compensated by Baf53b. Sci Rep 14059

 

Ahn, Jinwoo DeLucia, Maria Hao, Caili Hrecka, Kasia Monnie, Christina Skowronski, Jacek Zhou, Xiaohong (2017) HIV-1 Vpr protein directly loads helicase-like transcription factor (HLTF) onto the CRL4-DCAF1 E3 ubiquitin ligase. Journal of Biological Chemistry 21117-21127

 

Alterauge, D. Arzberger, T. Baumjohann, D. Edbauer, D. Farny, D. Feederle, R. Flatley, A. Greiling, J. Haass, C. Hermann, A. Klopstock, T. Kuhm, C. Lehmer, C. May, S. Michaelsen, M. Mori, K. Schludi, M. H. Schreiber, F. Zhou, Q. (2017) Antibodies inhibit transmission and aggregation of C9orf72 poly-GA dipeptide repeat proteins. EMBO Mol Med 687-702

 

Gao, G. Guo, D. Hou, P. Li, C. M. Zhou, J. (2017) Regulation of the Alternative Splicing and Function of Cyclin T1 by the Serine-Arginine-Rich Protein ASF/SF2. J Cell Biochem 4020-4032

 

Chiao, P. J. Fan, X. Fu, J. Ji, S. Ling, J. Qin, Y. Song, L. Yu, X. Zhou, H. Zhuang, Z. (2017) SOX9 activity is induced by oncogenic Kras to affect MDC1 and MCMs expression in pancreatic cancer. Oncogene

 

Feng, J. Hu, Z. Jiang, H. Yan, Z. Zhong, P. (2017) Dopamine Induces Oscillatory Activities in Human Midbrain Neurons with Parkin Mutations. Cell Rep 1033-1044

 

Wang, Y. Xu, J. Xu, M. Yuan, Y. Zhong, C. (2017) An APE1 inhibitor reveals critical roles of the redox function of APE1 in KSHV replication and pathogenic phenotypes. PLoS Pathog e1006289

 

Cao, M. Fan, L. Feng, X. Ge, H. Guo, Y. Harris, A. L. Lai, Y. Peng, Y. Song, J. Tao, L. Wang, Q. Wang, X. Zhao, Y. (2017) Non-junctional Cx32 mediates anti-apoptotic and pro-tumor effects via epidermal growth factor receptor in human cervical cancer cells. Cell Death Dis e2773

 

Ahearn, Joseph M. Cummins, Kaelyn C. Eisenberg, Evan Greene, Lois E. Rodriguez, Ramon Saidha, Sheela Silberman, Rebecca E. Zhao, Xiaohong (2017) Heat shock protein 104 (Hsp104)-mediated curing of [PSI+] yeast prions depends on both [PSI+] conformation and the properties of the Hsp104 homologs. Journal of Biological Chemistry 8630-8641

 

Ajibade, A. Li, Q. Liu, P. Long, T. Long, W. Ning, B. Tan, P. Wang, H. Y. Wang, R. F. Zhao, W. Zhu, Q. (2017) Tgfbr2 inactivation facilitates cellular plasticity and development of Pten-null prostate cancer. J Mol Cell Biol

 

Ahituv, N. Biton, A. Erle, D. J. Siegel, D. Tonqueze, O. L. Zaitlen, N. Zhao, W. (2017) CRISPR-Cas9-mediated functional dissection of 3\'-UTRs. Nucleic Acids Res 10800-10810

 

Pferdehirt, L. Segatori, L. Zhao, W. (2017) Quantitatively Predictable Control of Cellular Protein Levels through Proteasomal Degradation. ACS Synth Biol

 

Green, M. Loewenstein, P. M. Zhao, L. J. (2017) Adenovirus E1A TRRAP-targeting domain-mediated enhancement of MYC association with the NuA4 complex activates a panel of MYC target genes enriched for gene expression and ribosome biogenesis. Virology 172-179

 

Koues, O. I. Majumder, K. Oltz, E. M. Osipovich, O. Zhao, J. Y. (2017) Activation of Mouse Tcrb: Uncoupling RUNX1 Function from Its Cooperative Binding with ETS1. J Immunol 1131-1141

 

Bao, Y. Huang, Y. Huang, Z. Liu, W. Saffen, D. Shao, Z. Song, F. Sun, Y. Wang, Y. Zhao, J. Zuo, J. (2017) Functional analysis reveals that RBM10 mutations contribute to lung adenocarcinoma pathogenesis by deregulating splicing. Sci Rep 40488

 

Choi, K. Zhao, H. (2017) A CRISPR screen identifies genes controlling Etv2 threshold expression in murine hemangiogenic fate commitment. Nat Commun 541

 

Duong, W. Q. Gonyo, P. Hu, W. Kumar, S. Liu, Z. Miao, Q. R. Rana, U. Wang, B. Williams, C. L. Yang, Z. Zhao, B. (2017) The Nogo-B receptor promotes Ras plasma membrane localization and activation. Oncogene

 

Adoumie, M. Brannon, A. Crawford, H. C. Kane, K. T. Mathew, E. Pasca di Magliano, M. Vinta, A. Yan, W. Zhang, Y. (2017) Epithelial-Myeloid cell crosstalk regulates acinar cell plasticity and pancreatic remodeling in mice. Elife

 

Beatty, G. L. Flannagan, K. Li, D. Mathew, E. Mendez, F. M. Pasca di Magliano, M. Rhim, A. D. Simeone, D. M. Velez-Delgado, A. Zhang, Y. (2017) Myeloid cells are required for PD-1/PD-L1 checkpoint activation and the establishment of an immunosuppressive environment in pancreatic cancer. Gut 124-136

 

Kibaly, C. Law, P. Y. Loh, H. H. Xu, C. Zhang, Y. (2017) Temporal effect of manipulating NeuroD1 expression with the synthetic small molecule KHS101 on morphine contextual memory. Neuropharmacology 58-69

 

Call, M. Dong, F. Hayashi, Y. Kao, W. W. Liu, C. Y. Shiraishi, A. Wang, Y. C. Yuan, Y. Yuka, O. Zhang, J. Zhang, L. Zhang, Y. (2017) Generation and Characterization of a Novel Mouse Line, Keratocan-rtTA (KeraRT), for Corneal Stroma and Tendon Research. Invest Ophthalmol Vis Sci 4800-4808

 

Yuan, Z. Yue, L. Zhang, X. Zhang, Z. (2017) Establishment of a fluorescent in situ hybridization assay for imaging hepatitis B virus nucleic acids in cell culture models. Emerg Microbes Infect e98

 

Cha, I. H. Kim, H. S. Kim, K. Y. Yook, J. I. Zhang, X. Zheng, Z. (2017) Snail and Axin2 expression predict the malignant transformation of oral leukoplakia. Oral Oncol 48-55

 

Dong, A. Dong, X. Ernst, A. Federowicz, K. E. Haddad, D. Heerding, D. Li, Y. Liu, L. Makhnevych, T. Moffat, J. Nim, S. Sartori, M. A. Sidhu, S. S. Tong, Y. Yang, J. Zhang, W. (2017) Generation and Validation of Intracellular Ubiquitin Variant Inhibitors for USP7 and USP10. J Mol Biol 3546-3560

 

Chen, B. P. Hu, Q. Huang, J. Li, F. Liu, H. Ma, W. Rong, Y. Songyang, Z. Tang, M. Zhang, S. Zhang, T. Zhang, Z. Zhao, Y. (2017) Looping-out mechanism for resolution of replicative stress at telomeres. EMBO Rep 1412-1428

 

Song, Z. Zhang, S. (2017) Aio-Casilio: a robust CRISPR-Cas9-Pumilio system for chromosome labeling. J Mol Histol 293-299

 

Goodman, J. Gopal, P. Li, L. Nassour, I. Nguyen, L. H. Sehgal, A. Siegwart, D. J. Singal, A. G. Tu, H. C. Yopp, A. Zhang, S. Zhang, Y. Zhou, K. Zhu, H. (2017) Knockdown of Anillin Actin Binding Protein Blocks Cytokinesis in Hepatocytes and Reduces Liver Tumor Development in Mice Without Affecting Regeneration. Gastroenterology

 

Chen, Y. Gao, H. Liu, H. Sivakumar, S. Yang, L. Yu, H. Yuan, Z. Zhang, Q. (2017) Ska3 Phosphorylated by Cdk1 Binds Ndc80 and Recruits Ska to Kinetochores to Promote Mitotic Progression. Curr Biol 1477-1484 e4

 

Chen, S. Feng, X. H. Guan, K. L. Li, X. Liu, J. Liu, S. Meng, F. Plouffe, S. W. Qin, J. Wang, J. Wu, S. Xu, P. Zhang, Q. Zhao, B. Zhou, R. Zou, J. (2017) Hippo signalling governs cytosolic nucleic acid sensing through YAP/TAZ-mediated TBK1 blockade. Nat Cell Biol 362-374

 

Cohen, P. Macartney, T. Peggie, M. Zhang, J. (2017) Interleukin-1 and TRAF6-dependent activation of TAK1 in the absence of TAB2 and TAB3. Biochem J 2235-2248

 

Bae, S. Chen, D. Chu, C. Cui, R. Jiao, K. Li, B. Liu, R. Stringer-Reasor, E. Sun, L. Wang, L. Wei, S. Yang, W. H. Zhang, G. Zhang, W. (2017) MicroRNA-200c and microRNA- 141 are regulated by a FOXP3-KAT2B axis and associated with tumor metastasis in breast cancer. Breast Cancer Res 73

 

Caldarone, B. J. Cheng, J. Kozikowski, A. P. Lorello, P. J. McCorvy, J. D. Roth, B. L. Zhang, G. (2017) Discovery of N-Substituted (2-Phenylcyclopropyl)methylamines as Functionally Selective Serotonin 2C Receptor Agonists for Potential Use as Antipsychotic Medications. J Med Chem 6273-6288

 

Cui, J. Feng, J. W. Gray, A. Hardie, D. G. Hawley, S. A. Li, M. Li, T. Y. Lin, S. C. Lin, S. Y. Ma, T. Piao, H. L. Wang, Z. Wu, Y. Q. Ye, Z. Yin, H. Zhang, C. S. Zhu, M. Zong, Y. (2017) Fructose-1,6-bisphosphate and aldolase mediate glucose sensing by AMPK. Nature 112-116

 

Ananthanarayanan, A. Kim, K. Li, H. Liu, Z. Skamagki, M. Zhang, C. Zhao, R. (2017) Biological Significance of the Suppression of Oxidative Phosphorylation in Induced Pluripotent Stem Cells. Cell Rep 2058-2065

 

Chen, Xingcheng Chen, Yuanhong Dong, Jixin Stauffer, Seth Zeng, Yongji Zhou, Jiuli (2017) Cyclin-dependent kinase 1 (CDK1)-mediated mitotic phosphorylation of the transcriptional co-repressor Vgll4 inhibits its tumor-suppressing activity. Journal of Biological Chemistry 15028-15038

 

Bae, Y. Bertin, T. Campeau, P. M. Chen, R. Chen, Y. Dawson, B. C. Lee, B. H. Munivez, E. Tao, J. Zeng, H. C. (2017) MicroRNA miR-23a cluster promotes osteocyte differentiation by regulating TGF-beta signalling in osteoblasts. Nat Commun 15000

 

Bukau, B. Fink, C. A. Fleming, T. H. Herzig, S. Kniess, R. A. Loft, A. Mayer, M. Nawroth, P. P. Schmidt, L. Tyedmers, J. Zemva, J. (2017) Hormesis enables cells to handle accumulating toxic metabolites during increased energy flux. Redox Biol 674-686

 

Akalin, A. Birchmeier, C. Calviello, L. Chekulaeva, M. Ciolli Mattioli, C. Filipchyk, A. Franke, V. Imami, K. Mazzoni, E. O. McShane, E. Merino, E. Moreno-Estelles, M. Muller, T. Ohler, U. Peguero-Sanchez, E. Rajewsky, N. Selbach, M. van den Bruck, D. Woehler, A. Zappulo, A. (2017) RNA localization is a key determinant of neurite-enriched proteome. Nat Commun 583

 

Costa, M. Crespo, R. Dardenne, M. Goya, R. G. Lopez-Leon, M. Pardo, J. Reggiani, P. C. Zappa-Villar, M. F. (2017) A new adenovector system for implementing thymulin gene therapy for inflammatory disorders. Mol Immunol 180-187

 

Battulin, N. R. Fishman, V. S. Vasiliev, G. V. Yunusova, A. M. (2017) Deterministic versus stochastic model of reprogramming: new evidence from cellular barcoding technique. Open Biol

 

Barski, A. Charles Richard, J. L. Ogawa, A. Ogawa, Y. Yamada, N. Yue, M. (2017) Xist RNA repeat E is essential for ASH2L recruitment to the inactive X and regulates histone modifications and escape gene expression. PLoS Genet e1006890

 

Gao, P. Jiang, J. Liu, H. Qing, G. Yue, M. (2017) Oncogenic MYC Activates a Feedforward Regulatory Loop Promoting Essential Amino Acid Metabolism and Tumorigenesis. Cell Rep 3819-3832

 

Gou, X. Li, Y. Wicksteed, B. Wu, X. Yue, J. (2017) Engineered Epidermal Progenitor Cells Can Correct Diet-Induced Obesity and Diabetes. Cell Stem Cell 256-263 e4

 

Bautch, V. L. Kushner, E. J. Ruter, D. L. Yu, Z. (2017) Excess centrosomes induce p53-dependent senescence without DNA damage in endothelial cells. FASEB J 4295-4304

 

Ma, Y. Wang, H. Yu, T. (2017) EpCAM Intracellular Domain Promotes Porcine Cell Reprogramming by Upregulation of Pluripotent Gene Expression via Beta-catenin Signaling. Sci Rep 46315

 

Kong, L. Li, S. Luo, M. Ma, L. Mao, W. Mei, Q. Tong, C. Xue, X. Yu, Q. Yu, X. Yu, X. (2017) Regulation of SESAME-mediated H3T11 phosphorylation by glycolytic enzymes and metabolites. PLoS One e0175576

 

Bae, S. Choi, J. H. Hohng, S. Kaang, B. K. Sacktor, T. C. Shim, J. Uhm, H. Yu, N. K. (2017) Increased PKMzeta activity impedes lateral movement of GluA2-containing AMPA receptors. Mol Brain 56

 

Hasegawa, Atsushi Hayashi, Makiko Kaneko, Hiroshi Moriguchi, Takashi Nezu, Masahiro Saya, Hideyuki Shimizu, Ritsuko Yamamoto, Masayuki Yu, Lei (2017) Reducing Inflammatory Cytokine Production from Renal Collecting Duct Cells by Inhibiting GATA2 Ameliorates Acute Kidney Injury. Molecular and Cellular Biology

 

Ahangari, F. Arrojo, E. Drigo R. Aurelien, N. Bianco, A. C. de Castro, J. P. W. DeIuliis, G. Gan, Y. Graham, M. Herazo-Maya, J. D. Herzog, E. L. Homer, R. J. Ibarra, G. H. Kaminski, N. Lee, P. J. Liu, X. Mannam, P. Scanlan, T. S. Srivastava, A. Tzouvelekis, A. Wang, R. Woolard, T. Yu, G. (2017) Thyroid hormone inhibits lung fibrosis in mice by improving epithelial mitochondrial function. Nat Med

 

Cao, M. Guo, J. Jiang, Y. Liu, D. Liu, X. Lu, L. Qiao, Y. Van Dyke, T. Wang, F. Yang, Z. Yao, X. Yu, F. (2017) Aurora-A promotes the establishment of spindle assembly checkpoint by priming the Haspin-Aurora-B feedback loop in late G2 phase. Cell Discov 16049

 

An, T. Gong, Y. Kong, L. Li, Y. Liu, J. Wang, M. Yu, C. Zhou, H. Zhu, H. (2017) Star-PAP, a poly(A) polymerase, functions as a tumor suppressor in an orthotopic human breast cancer model. Cell Death Dis e2582

 

Bellefroid, E. J. Gennet, N. Keruzore, M. Li, M. Nan, X. Young, F. I. (2017) The doublesex-related Dmrta2 safeguards neural progenitor maintenance involving transcriptional regulation of Hes1. Proc Natl Acad Sci U S A E5599-E5607

 

Adhikary, G. Blumenberg, M. Crumrine, D. Eckert, R. L. Elias, P. M. Rorke, E. A. Young, C. A. (2017) Embryonic AP1 Transcription Factor Deficiency Causes a Collodion Baby-Like Phenotype. J Invest Dermatol 1868-1877

 

Dammann, P. Keyvani, K. Kreitschmann-Andermahr, I. Sure, U. You, C. Zhao, K. Zhu, Y. (2017) EphB4 forward signalling mediates angiogenesis caused by CCM3/PDCD10-ablation. J Cell Mol Med 1848-1858

 

Mino, T. Nakatsuka, Y. Ori, D. Suzuki, Y. Takeuchi, O. Tsujimura, T. Uehata, T. Vandenbon, A. Yoshinaga, M. (2017) Regnase-1 Maintains Iron Homeostasis via the Degradation of Transferrin Receptor 1 and Prolyl-Hydroxylase-Domain-Containing Protein 3 mRNAs. Cell Rep 1614-1630

 

Hosokawa, H. Matsuo, N. Yoshii, T. (2017) Pharmacogenetic reactivation of the original engram evokes an extinguished fear memory. Neuropharmacology 1-9

 

Awaya, T. Era, T. Heike, T. Jonouchi, T. Kimura, R. Kimura, S. Sakurai, H. Yoshida, T. (2017) A Skeletal Muscle Model of Infantile-onset Pompe Disease with Patient-specific iPS Cells. Sci Rep 13473

 

Carromeu, C. Kwon, O. Muotri, A. Schachner, M. Yoo, M. (2017) The L1 adhesion molecule normalizes neuritogenesis in Rett syndrome-derived neural precursor cells. Biochem Biophys Res Commun 504-510

 

Inokuchi, K. Kato, F. Matsuo, M. Nagase, M. Nishizono, H. Nomoto, M. Ohkawa, N. Okubo-Suzuki, R. Sasahara, M. Suzuki, A. Takahashi, Y. Tsujimura, S. Watabe, A. M. Yokose, J. (2017) Overlapping memory trace indispensable for linking, but not recalling, individual memories. Science 398-403

 

Attar, M. A. Burns, T. F. Cades, J. Chatley, S. N. Chatterjee, S. Cho, Y. J. Engh, J. A. Ewald, A. J. Huang, E. H. Khetarpal, S. K. Mazzacurati, L. Neumann, N. M. Nugent, K. Rudin, C. M. Somasundaram, A. Tran, P. T. Wang, H. Yochum, Z. A. (2017) A First-in-Class TWIST1 Inhibitor with Activity in Oncogene-Driven Lung Cancer. Mol Cancer Res 1764-1776

 

Cai, Xiaoqing de Waal, Parker W. He, Yuanzheng Jiang, Yi Melcher, Karsten Wang, Ming-Wei Xu, H. Eric Yang, Dehua Yin, Yanting Zhao, Li-Hua (2017) Rearrangement of a polar core provides a conserved mechanism for constitutive activation of class B G protein-coupled receptors. Journal of Biological Chemistry 9865-9881

 

Her, G. M. Hsu, C. C. Lai, C. Y. Lin, C. Y. Lo, C. P. Yeh, K. Y. (2017) ATF4 overexpression induces early onset of hyperlipidaemia and hepatic steatosis and enhances adipogenesis in zebrafish. Sci Rep 16362

 

Fan, Y. Mann, M. J. Yang, Y. L. Yeh, C. C. (2017) Atrial ERK1/2 activation in the embryo leads to incomplete Septal closure: a novel mouse model of atrial Septal defect. J Biomed Sci 89

 

Chen, E. R. Nilsen, T. W. Ye, F. (2017) Kaposi\'s Sarcoma-Associated Herpesvirus Utilizes and Manipulates RNA N(6)-Adenosine Methylation To Promote Lytic Replication. J Virol

 

Castellanos, E. R. Dixit, V. M. Doerner, K. Haakonsen, D. L. Martinez-Martin, N. Matsumoto, M. L. Rape, M. Wang, N. Werner, A. Yang, X. W. Yau, R. G. (2017) Assembly and Function of Heterotypic Ubiquitin Chains in Cell-Cycle and Protein Quality Control. Cell 918-933 e20

 

Clatterbuck-Soper, S. F. Jackrel, M. E. Mili, S. Shorter, J. Yasuda, K. (2017) FUS inclusions disrupt RNA localization by sequestering kinesin-1 and inhibiting microtubule detyrosination. J Cell Biol 1015-1034

 

Barbacid, M. Baumert, H. Campbell, N. M. Cecchi, F. Chang, M. T. de Stanchina, E. Drosten, M. Hembrough, T. Michels, J. Miles, L. Rodrik-Outmezguine, V. S. Rosen, N. Solit, D. B. Tao, A. Taylor, B. S. Torres, N. M. Yaeger, R. Yao, Z. Zhao, H. (2017) Tumours with class 3 BRAF mutants are sensitive to the inhibition of activated RAS. Nature 234-238

 

Cui, Z. Dang, Y. Fei, F. Li, Q. Liu, L. Liu, X. Sun, S. Wang, J. Wang, X. Wang, Y. Wu, J. Yao, Y. Yu, M. Zhang, R. (2017) Screening in larval zebrafish reveals tissue-specific distribution of fifteen fluorescent compounds. Dis Model Mech 1155-1164

 

Chang, C. Chou, Y. C. Fujita, T. Ikeda, S. Iwasawa, Y. Kaname, Y. Kato, H. Noda, T. Otakaki, Y. Qin, M. Shindo, K. Takeuchi, F. Tsukamoto, Y. Wakita, T. Watashi, K. Yao, W. L. (2017) Establishment of a human hepatocellular cell line capable of maintaining long-term replication of hepatitis B virus. Int Immunol 109-120

 

Guo, J. Song, L. Yao, Q. Yu, C. Zhang, K. Zhang, X. (2017) Wnt/beta-catenin signaling in osteoblasts regulates global energy metabolism. Bone 175-183

 

Ding, W. Durando, M. Gao, Y. Mutter-Rottmayer, L. Ramsden, D. Tanoue, Y. Tateishi, S. Vaziri, C. Wyatt, D. Yang, Y. Zlatanou, A. (2017) DNA repair factor RAD18 and DNA polymerase Polkappa confer tolerance of oncogenic DNA replication stress. J Cell Biol 3097-3115

 

Carstens, R. P. Yang, Y. (2017) Alternative splicing regulates distinct subcellular localization of Epithelial splicing regulatory protein 1 (Esrp1) isoforms. Sci Rep 3848

 

Gong, Z. Yan, C. Yang, Q. Yin, C. (2017) Serotonin Activated Hepatic Stellate Cells Contribute to Sex Disparity in Hepatocellular Carcinoma. Cell Mol Gastroenterol Hepatol 484-499

 

Gong, Z. Yan, C. Yang, Q. (2017) Activation of liver stromal cells is associated with male-biased liver tumor initiation in xmrk and Myc transgenic zebrafish. Sci Rep 10315

 

Ahlenius, H. Ang, C. E. Buylla, A. A. Chanda, S. Chang, H. Y. Flores, Q. Haag, D. Janas, J. A. Li, M. Mall, M. Marro, S. Ng, Y. H. Rubenstein, J. L. Sudhof, T. C. Tang, Y. Wapinski, O. Wernig, M. Yang, N. (2017) Generation of pure GABAergic neurons by transcription factor programming. Nat Methods 621-628

 

Chen, F. Gao, H. Liu, L. Mathison, M. Mo, Q. Pinnamaneni, J. P. Rosengart, T. Sanagasetti, D. Singh, V. P. Wang, K. Yang, J. Yang, L. Zhang, Q. (2017) The stem cell factor SALL4 is an essential transcriptional regulator in mixed lineage leukemia-rearranged leukemogenesis. J Hematol Oncol 159

 

Brazil, D. P. Hemmings, B. A. Hong, S. Kim, S. H. Lee, H. Li, Y. Park, J. Park, J. Piao, L. Shin, S. Shin, S. Y. Tran, Q. Yang, K. J. (2017) Modulation of PI3K/PTEN Pathway Does Not Affect Catalytic Activity of PDK1 in Jurkat Cells. Anticancer Res 5415-5423

 

Antunes, L. Bussell, J. Campos, L. S. Chen, X. Eckersley-Maslin, M. A. Fu, B. Gao, X. Gottgens, B. Kolodziejczyk, A. A. Lan, G. Liu, P. Lu, L. Masaki, H. Nakauchi, H. Ramirez-Solis, R. Reik, W. Ryan, D. J. Tam, P. P. L. Tanaka, Y. Teichmann, S. A. Tsang, J. C. Wang, C. Wang, J. Wang, W. White, J. Wilkinson, A. C. Woods, M. Yang, F. Yang, J. Yu, Y. Zhong, Z. Zhu, Z. Zou, X. (2017) Establishment of mouse expanded potential stem cells. Nature 393-397

 

Grossmann, A. H. Holmen, S. L. Kim, K. H. Kircher, D. A. Robinson, J. P. VanBrocklin, M. W. Yang, H. (2017) Activated MEK cooperates with Cdkn2a and Pten loss to promote the development and maintenance of melanoma. Oncogene

 

Cebotaru, Liudmila Cebotaru, Valeriu Guggino, William B. Liu, Qiangni Yanda, Murali K. (2017) Histone deacetylase 6 inhibition reduces cysts by decreasing cAMP and Ca2+ in knock-out mouse models of polycystic kidney disease. Journal of Biological Chemistry 17897-17908

 

Cebotaru, L. Liu, Q. Yanda, M. K. (2017) An inhibitor of histone deacetylase 6 activity, ACY-1215, reduces cAMP and cyst growth in polycystic kidney disease. Am J Physiol Renal Physiol F997-F1004

 

Harikumar, Kaleeckal G. Melcher, Karsten Miller, Laurence J. Xu, H. Eric Xu, Ting-Hai Yan, Yan (2017) Dimerization of the transmembrane domain of amyloid precursor protein is determined by residues around the ?-secretase cleavage sites. Journal of Biological Chemistry 15826-15837

 

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