Leadership In Controlled Gene Expression

2007

Adachi, K., Soeta-Saneyoshi, C., Sagara, H., and Iwakura, Y. (2007). Crucial Role of Bysl in Mammalian Preimplantation Development as an Integral Factor for 40S Ribosome Biogenesis. Mol Cell Biol 27, 2202-2214.

 

Adair, J. E., Maloney, S. C., Dement, G. A., Wertzler, K. J., Smerdon, M. J., and Reeves, R. (2007). High-Mobility Group A1 Proteins Inhibit Expression of Nucleotide Excision Repair Factor Xeroderma Pigmentosum Group A. Cancer Res 67, 6044-6052.

 

Agarwal, M. K., Amin, A. R. M. R., and Agarwal, M. L. (2007). DNA Replication Licensing Factor Minichromosome Maintenance Deficient 5 Rescues p53-Mediated Growth Arrest. Cancer Res 67, 116-121.

 

Aiba, A., and Nakao, H. (2007). Conditional mutant mice using tetracycline-controlled gene expression system in the brain. Neuroscience Research 58, 113.

 

Alawi, F., and Lee, M. N. (2007). DKC1 is a direct and conserved transcriptional target of c-MYC. Biochemical and Biophysical Research Communications 362, 893.

 

Aleksic, T., Baumann, B., Wagner, M., Adler, G., Wirth, T., and Weber, C. K. (2007). Cellular immune reaction in the pancreas is induced by constitutively active I{kappa}B kinase-2. Gut 56, 227-236.

 

Alvarez-Breckenridge, C. A., Waite, K. A., and Eng, C. (2007). PTEN regulates phospholipase D and phospholipase C. Human Molecular Genetics 16, 1157.

 

Alvarez-Saavedra, M., Saez, M. A., Kang, D., Zoghbi, H. Y., and Young, J. I. (2007). Cell-specific expression of wild-type MeCP2 in mouse models of Rett syndrome yields insight about pathogenesis. Hum Mol Genet 16, 2315-2325.

 

Amazit, L., Pasini, L., Szafran, A. T., Berno, V., Wu, R.-C., Mielke, M., Jones, E. D., Mancini, M. G., Hinojos, C. A., O'Malley, B. W., and Mancini, M. A. (2007). Regulation of SRC-3 Intercompartmental Dynamics by Estrogen Receptor and Phosphorylation. Molecular and Cellular Biology 27, 6913.

 

Amente, S., Gargano, B., Diolaiti, D., Della Valle, G., Lania, L., and Majello, B. (2007). p14ARF interacts with N-Myc and inhibits its transcriptional activity. FEBS Letters 581, 821.

 

Amorino, G. P., Deeble, P. D., and Parsons, S. J. (2007). Neurotensin stimulates mitogenesis of prostate cancer cells through a novel c-Src//Stat5b pathway. Oncogene 26, 745.

 

Anantha, R. W., Vassin, V. M., and Borowiec, J. A. (2007). Sequential and Synergistic Modification of Human RPA Stimulates Chromosomal DNA Repair. Journal of Biological Chemistry 282, 35910.

 

Anelli, T., Ceppi, S., Bergamelli, L., Cortini, M., Masciarelli, S., Valetti, C., and Sitia, R. (2007). Sequential steps and checkpoints in the early exocytic compartment during secretory IgM biogenesis. Embo J 26, 4177-4188.

 

Angelow, S., El-Husseini, R., Kanzawa, S. A., and Yu, A. S. L. (2007). Renal localization and function of the tight junction protein, claudin-19. Am J Physiol Renal Physiol 293, F166-177.

 

Arasaki, K., Tani, K., Yoshimori, T., Stephens, D. J., and Tagaya, M. (2007). Nordihydroguaiaretic Acid Affects Multiple Dynein-Dynactin Functions in Interphase and Mitotic Cells. Mol Pharmacol %R 101124/mol106029611 71, 454-460.

 

Aron, R., Higurashi, T., Sahi, C., and Craig, E. A. (2007). J-protein co-chaperone Sis1 required for generation of [RNQ+] seeds necessary for prion propagation. Embo J 26, 3794-3803.

 

Arvanitis, D. N., Ducatenzeiler, A., Ou, J. N., Grodstein, E., Andrews, S. D., Tendulkar, S. R., Ribeiro-da-Silva, A., Szyf, M., and Cuello, A. C. (2007). High intracellular concentrations of amyloid-beta block nuclear translocation of phosphorylated CREB. Journal of Neurochemistry 103, 216-228.

 

Astrakhan, A., Omori, M., Nguyen, T., Becker-Herman, S., Iseki, M., Aye, T., Hudkins, K., Dooley, J., Farr, A., Alpers, C. E., et al. (2007). Local increase in thymic stromal lymphopoietin induces systemic alterations in B cell development. Nat Immunol 8, 522.

 

Baguet, A., Degot, S., Cougot, N., Bertrand, E., Chenard, M.-P., Wendling, C., Kessler, P., Le Hir, H., Rio, M.-C., and Tomasetto, C. (2007). The exon-junction-complex-component metastatic lymph node 51 functions in stress-granule assembly. Journal of Cell Science 120, 2774.

 

Balasubramanyam, A., Mersmann, H., Jahoor, F., Phillips, T. M., Sekhar, R. V., Schubert, U., Brar, B., Iyer, D., Smith, E. O. B., Takahashi, H., et al. (2007). Effects of transgenic expression of HIV-1 Vpr on lipid and energy metabolism in mice. Am J Physiol Endocrinol Metab 292, E40-48.

 

Balducci, E., Micossi, L. G., Soldaini, E., and Rappuoli, R. (2007). Expression and selective up-regulation of toxin-related mono ADP-ribosyltransferases by pathogen-associated molecular patterns in alveolar epithelial cells. FEBS Letters 581, 4199.

 

Baliko, F., Bright, T., Poon, R., Cohen, B., Egan, S. E., and Alman, B. A. (2007). Inhibition of Notch Signaling Induces Neural Differentiation in Ewing Sarcoma. American Journal of Pathology 170, 1686.

 

Bandyopadhyay, D., Curry, J. L., Lin, Q., Richards, H. W., Chen, D., Hornsby, P. J., Timchenko, N. A., and Medrano, E. E. (2007). Dynamic assembly of chromatin complexes during cellular senescence: implications for the growth arrest of human melanocytic nevi. Aging Cell 6, 577-591.

 

Bansal, P., and Lazo, J. S. (2007). Induction of Cdc25B Regulates Cell Cycle Resumption after Genotoxic Stress. Cancer Res 67, 3356-3363.

 

Barthelme, D., Scheele, U., Dinkelaker, S., Janoschka, A., MacMillan, F., Albers, S.-V., Driessen, A. J. M., Stagni, M. S., Bill, E., Meyer-Klaucke, W., et al. (2007). Structural Organization of Essential Iron-Sulfur Clusters in the Evolutionarily Highly Conserved ATP-binding Cassette Protein ABCE1. Journal of Biological Chemistry 282, 14598.

 

Baumann, B., Wagner, M., Aleksic, T., von Wichert, G., Weber, C. K., Adler, G., and Wirth, T. (2007). Constitutive IKK2 activation in acinar cells is sufficient to induce pancreatitis in vivo. J Clin Invest 117, 1502-1513.

 

Beach, D., Gonen, R., Bogin, Y., Reischl, I. G., and Yablonski, D. (2007). Dual Role of SLP-76 in Mediating T Cell Receptor-induced Activation of Phospholipase C-{gamma}1. Journal of Biological Chemistry 282, 2937.

 

Beierle, E. A., Trujillo, A., Nagaram, A., Kurenova, E. V., Finch, R., Ma, X., Vella, J., Cance, W. G., and Golubovskaya, V. M. (2007). N-MYC Regulates Focal Adhesion Kinase Expression in Human Neuroblastoma. Journal of Biological Chemistry 282, 12503.

 

Bentle, M. S., Reinicke, K. E., Dong, Y., Bey, E. A., and Boothman, D. A. (2007). Nonhomologous End Joining Is Essential for Cellular Resistance to the Novel Antitumor Agent, {beta}-Lapachone. Cancer Res %R 101158/0008-5472CAN-07-0935 67, 6936-6945.

 

Berger, A. B., Decourty, L., Badis, G., Nehrbass, U., Jacquier, A., and Gadal, O. (2007). Hmo1 Is Required for TOR-Dependent Regulation of Ribosomal Protein Gene Transcription. Molecular and Cellular Biology 27, 8015.

 

Berger, Z., Roder, H., Hanna, A., Carlson, A., Rangachari, V., Yue, M., Wszolek, Z., Ashe, K., Knight, J., Dickson, D., et al. (2007). Accumulation of Pathological Tau Species and Memory Loss in a Conditional Model of Tauopathy. J Neurosci 27, 3650-3662.

 

Berkova, Z., Crawford, S. E., Blutt, S. E., Morris, A. P., and Estes, M. K. (2007). Expression of Rotavirus NSP4 Alters the Actin Network Organization through the Actin Remodeling Protein Cofilin. J Virol 81, 3545-3553.

 

Bernardo, M. V., Yelo, E., Gimeno, L., Campillo, J. A., and Parrado, A. (2007). Identification of apoptosis-related PLZF target genes. Biochemical and Biophysical Research Communications 359, 317.

 

Besnard, V., Xu, Y., and Whitsett, J. A. (2007). Sterol response element binding protein and thyroid transcription factor-1 (Nkx2.1) regulate Abca3 gene expression. Am J Physiol Lung Cell Mol Physiol 293, L1395-1405.

 

Bezy, O., Vernochet, C., Gesta, S., Farmer, S. R., and Kahn, C. R. (2007). TRB3 Blocks Adipocyte Differentiation through the Inhibition of C/EBP{beta} Transcriptional Activity. Molecular and Cellular Biology 27, 6818.

 

Bhana, S., and Lloyd, D. R. (2007). The role of p53 in DNA damage-mediated cytotoxicity overrides its ability to regulate nucleotide excision repair in human fibroblasts. Mutagenesis gem041.

 

Bharadwaj, A. G., Rector, K., and Simpson, M. A. (2007). Inducible Hyaluronan Production Reveals Differential Effects on Prostate Tumor Cell Growth and Tumor Angiogenesis. Journal of Biological Chemistry 282, 20561.

 

Binne, U. K., Classon, M. K., Dick, F. A., Wei, W., Rape, M., Kaelin, W. G., Naar, A. M., and Dyson, N. J. (2007). Retinoblastoma protein and anaphase-promoting complex physically interact and functionally cooperate during cell-cycle exit. Nat Cell Biol 9, 225.

 

Blesch, A., and Tuszynski, M. H. (2007). Transient Growth Factor Delivery Sustains Regenerated Axons after Spinal Cord Injury. Journal of Neuroscience 27, 10535.

 

Boily, G., Larose, J., Langlois, S., and Sinnett, D. (2007). Identification of transcripts modulated by ETV6 expression. Br J Haematol 136, 48-62.

 

Boutros, R., Lobjois, V., and Ducommun, B. (2007). CDC25B Involvement in the Centrosome Duplication Cycle and in Microtubule Nucleation. Cancer Research 67, 11557.

 

Boyer, F., and Dreyer, J.-L. (2007). Alpha-synuclein in the nucleus accumbens induces changes in cocaine behaviour in rats. European Journal of Neuroscience 26, 2764.

 

Braet, C., Stephan, H., Dobbie, I. M., Togashi, D. M., Ryder, A. G., Foldes-Papp, Z., Lowndes, N., and Nasheuer, H. P. (2007). Mobility and distribution of replication protein A in living cells using fluorescence correlation spectroscopy. Experimental and Molecular Pathology 82, 156.

 

Brass, V., Pal, Z., Sapay, N., Deleage, G., Blum, H. E., Penin, F., and Moradpour, D. (2007). Conserved Determinants for Membrane Association of Nonstructural Protein 5A from Hepatitis C Virus and Related Viruses. J Virol 81, 2745-2757.

 

Brengues, M., and Parker, R. (2007). Accumulation of Polyadenylated mRNA, Pab1p, eIF4E, and eIF4G with P-Bodies in Saccharomyces cerevisiae. Mol Biol Cell 18, 2592-2602.

 

Brennand, K., Huangfu, D., and Melton, D. (2007). All beta; Cells Contribute Equally to Islet Growth and Maintenance. PLoS Biology 5, e163.

 

Brisson, M., Foster, C., Wipf, P., Joo, B., Tomko, R. J., Jr., Nguyen, T., and Lazo, J. S. (2007). Independent Mechanistic Inhibition of Cdc25 Phosphatases by a Natural Product Caulibugulone. Mol Pharmacol %R 101124/mol106028589 71, 184-192.

 

Brough, R., Papanastasiou, A., and Porter, A. (2007). Stringent and reproducible tetracycline-regulated transgene expression by site-specific insertion at chromosomal loci with pre-characterised induction characteristics. BMC Molecular Biology 8, 30.

 

Brown, L., Ongusaha, P. P., Kim, H. G., Nuti, S., Mandinova, A., Lee, J. W., Khosravi-Far, R., Aaronson, S. A., and Lee, S. W. (2007). CDIP, a novel pro-apoptotic gene, regulates TNFalpha-mediated apoptosis in a p53-dependent manner. Embo J 26, 3410-3422.

 

Bry, K., Whitsett, J. A., and Lappalainen, U. (2007). IL-1beta Disrupts Postnatal Lung Morphogenesis in the Mouse. Am J Respir Cell Mol Biol 36, 32-42.

 

Burkard, N., Rokita, A. G., Kaufmann, S. G., Hallhuber, M., Wu, R., Hu, K., Hofmann, U., Bonz, A., Frantz, S., Cartwright, E. J., et al. (2007). Conditional Neuronal Nitric Oxide Synthase Overexpression Impairs Myocardial Contractility. Circulation Research 100, e32.

 

Cai, L., Das, B., and Brown, D. D. (2007). Changing a limb muscle growth program into a resorption program. Developmental Biology 304, 260.

 

Camargo, F. D., Gokhale, S., Johnnidis, J. B., Fu, D., Bell, G. W., Jaenisch, R., and Brummelkamp, T. R. (2007). YAP1 Increases Organ Size and Expands Undifferentiated Progenitor Cells. Current Biology 17, 2054.

 

Candi, E., Rufini, A., Terrinoni, A., Giamboi-Miraglia, A., Lena, A. M., Mantovani, R., Knight, R., and Melino, G. (2007). {Delta}Np63 regulates thymic development through enhanced expression of FgfR2 and Jag2. Proceedings of the National Academy of Sciences 104, 11999-12004.

 

Candolfi, M., Pluhar, G. E., Kroeger, K., Puntel, M., Curtin, J., Barcia, C., Muhammad, A. K. M. G., Xiong, W., Liu, C., Mondkar, S., et al. (2007). Optimization of adenoviral vector-mediated transgene expression in the canine brain in vivo, and in canine glioma cells in vitro. Neuro-Oncology 9, 245.

 

Cante-Barrett, K., Winslow, M. M., and Crabtree, G. R. (2007). Selective Role of NFATc3 in Positive Selection of Thymocytes. The Journal of Immunology 179, 103.

 

Cao, L., Dhilla, A., Mukai, J., Blazeski, R., Lodovichi, C., Mason, C. A., and Gogos, J. A. (2007). Genetic Modulation of BDNF Signaling Affects the Outcome of Axonal Competition In Vivo. Current Biology 17, 911.

 

Capowski, E. E., Schneider, B. L., Ebert, A. D., Seehus, C. R., Szulc, J., Zufferey, R., Aebischer, P., and Svendsen, C. N. (2007). Lentiviral vector-mediated genetic modification of human neural progenitor cells for ex vivo gene therapy. Journal of Neuroscience Methods 163, 338.

 

Carrillo, J., Garcia-Aragoncillo, E., Azorin, D., Agra, N., Sastre, A., Gonzalez-Mediero, I., Garcia-Miguel, P., Pestana, A., Gallego, S., Segura, D., and Alonso, J. (2007). Cholecystokinin Down-Regulation by RNA Interference Impairs Ewing Tumor Growth. Clin Cancer Res 13, 2429-2440.

 

Casper, K. B., Jones, K., and McCarthy, K. D. (2007). Characterization of astrocyte-specific conditional knockouts. genesis 45, 292-299.

 

Cawthorne, C., Swindell, R., Stratford, I. J., Dive, C., and Welman, A. (2007). Comparison of Doxycycline Delivery Methods for Tet-Inducible Gene Expression in a Subcutaneous Xenograft Model. J Biomol Tech 18, 120-123.

 

Ceteci, F., Ceteci, S., Karreman, C., Kramer, B. W., Asan, E., Gotz, R., and Rapp, U. R. (2007). Disruption of Tumor Cell Adhesion Promotes Angiogenic Switch and Progression to Micrometastasis in RAF-Driven Murine Lung Cancer. Cancer Cell 12, 145.

 

Chan, W. M., and Poon, R. Y. C. (2007). The p53 Isoform {Delta}p53 Lacks Intrinsic Transcriptional Activity and Reveals the Critical Role of Nuclear Import in Dominant-Negative Activity. Cancer Res 67, 1959-1969.

 

Chang, X., Fan, Y., Karyala, S., Schwemberger, S., Tomlinson, C. R., Sartor, M. A., and Puga, A. (2007). Ligand-Independent Regulation of Transforming Growth Factor {beta}1 Expression and Cell Cycle Progression by the Aryl Hydrocarbon Receptor. Molecular and Cellular Biology 27, 6127.

 

Chaturvedi, A., Battmer, K., Schaefer, D., Ganser, A., Eder, M., and Scherr, M. (2007). Comparison between Molecularly Defined and Conventional Therapeutics in a Conditional BCR-ABL Cell Culture Model. Oligonucleotides 17, 22-34.

 

Chelur, D. S., and Chalfie, M. (2007). From the Cover: Targeted cell killing by reconstituted caspases. PNAS 104, 2283-2288.

 

Chen, G., Fillebeen, C., Wang, J., and Pantopoulos, K. (2007). Overexpression of iron regulatory protein 1 suppresses growth of tumor xenografts. Carcinogenesis 28, 785-791.

 

Chen, M., Granger, A. J., VanBrocklin, M. W., Payne, W. S., Hunt, H., Zhang, H., Dodgson, J. B., and Holmen, S. L. (2007). Inhibition of avian leukosis virus replication by vector-based RNA interference. Virology 365, 464.

 

Chen, Z., Benureau, Y., Rijnbrand, R., Yi, J., Wang, T., Warter, L., Lanford, R. E., Weinman, S. A., Lemon, S. M., Martin, A., and Li, K. (2007). GB Virus B Disrupts RIG-I Signaling by NS3/4A-Mediated Cleavage of the Adaptor Protein MAVS. J Virol 81, 964-976.

 

Chen, Z., Rijnbrand, R., Jangra, R. K., Devaraj, S. G., Qu, L., Ma, Y., Lemon, S. M., and Li, K. (2007). Ubiquitination and proteasomal degradation of interferon regulatory factor-3 induced by Npro from a cytopathic bovine viral diarrhea virus. Virology 366, 277.

 

Cheng, D.-s., Han, W., Chen, S. M., Sherrill, T. P., Chont, M., Park, G.-Y., Sheller, J. R., Polosukhin, V. V., Christman, J. W., Yull, F. E., and Blackwell, T. S. (2007). Airway Epithelium Controls Lung Inflammation and Injury through the NF-{kappa}B Pathway. J Immunol 178, 6504-6513.

 

Chhipa, R. R., Kumari, R., Upadhyay, A. K., and Bhat, M. K. (2007). Abrogation of p53 by its antisense in MCF-7 breast carcinoma cells increases cyclin D1 via activation of Akt and promotion of cell proliferation. Experimental Cell Research 313, 3945.

 

Ching, S., Zhang, H., Belevych, N., He, L., Lai, W., Pu, X.-a., Jaeger, L. B., Chen, Q., and Quan, N. (2007). Endothelial-Specific Knockdown of Interleukin-1 (IL-1) Type 1 Receptor Differentially Alters CNS Responses to IL-1 Depending on Its Route of Administration. Journal of Neuroscience 27, 10476.

 

Chinta, S. J., Kumar, M. J., Hsu, M., Rajagopalan, S., Kaur, D., Rane, A., Nicholls, D. G., Choi, J., and Andersen, J. K. (2007). Inducible Alterations of Glutathione Levels in Adult Dopaminergic Midbrain Neurons Result in Nigrostriatal Degeneration. Journal of Neuroscience 27, 13997.

 

Choudhari, S. R., Khan, M. A., Harris, G., Picker, D., Jacob, G. S., Block, T., and Shailubhai, K. (2007). Deactivation of Akt and STAT3 signaling promotes apoptosis, inhibits proliferation, and enhances the sensitivity of hepatocellular carcinoma cells to an anticancer agent, Atiprimod. Mol Cancer Ther 6, 112-121.

 

Choudhuri, T., Verma, S. C., Lan, K., Murakami, M., and Robertson, E. S. (2007). The ATM/ATR Signaling Effector Chk2 Is Targeted by Epstein-Barr Virus Nuclear Antigen 3C To Release the G2/M Cell Cycle Block. J Virol 81, 6718-6730.

 

Christen, V., Duong, F., Bernsmeier, C., Sun, D., Nassal, M., and Heim, M. H. (2007). Inhibition of Alpha Interferon Signaling by Hepatitis B Virus. J Virol 81, 159-165.

 

Christophersen, N. S., Gronborg, M., Petersen, T. N., Fjord-Larsen, L., Jorgensen, J. R., Juliusson, B., Blom, N., Rosenblad, C., and Brundin, P. (2007). Midbrain expression of Delta-like 1 homologue is regulated by GDNF and is associated with dopaminergic differentiation. Experimental Neurology 204, 791.

 

Chtarto, A., Yang, X., Bockstael, O., Melas, C., Blum, D., Lehtonen, E., Abeloos, L., Jaspar, J. M., Levivier, M., Brotchi, J., et al. (2007). Controlled delivery of glial cell line-derived neurotrophic factor by a single tetracycline-inducible AAV vector. Experimental Neurology 204, 387.

 

Ciccaglione, A. R., Stellacci, E., Marcantonio, C., Muto, V., Equestre, M., Marsili, G., Rapicetta, M., and Battistini, A. (2007). Repression of Interferon Regulatory Factor 1 by Hepatitis C Virus Core Protein Results in Inhibition of Antiviral and Immunomodulatory Genes. J Virol 81, 202-214.

 

Ciesla, M., Towpik, J., Graczyk, D., Oficjalska-Pham, D., Harismendy, O., Suleau, A., Balicki, K., Conesa, C., Lefebvre, O., and Boguta, M. (2007). Maf1 Is Involved in Coupling Carbon Metabolism to RNA Polymerase III Transcription. Molecular and Cellular Biology 27, 7693.

 

Clement, V., Sanchez, P., de Tribolet, N., Radovanovic, I., and Ruiz i Altaba, A. (2007). HEDGEHOG-GLI1 Signaling Regulates Human Glioma Growth, Cancer Stem Cell Self-Renewal, and Tumorigenicity. Current Biology 17, 165.

 

Cohen, B., Ziv, K., Plaks, V., Israely, T., Kalchenko, V., Harmelin, A., Benjamin, L. E., and Neeman, M. (2007). MRI detection of transcriptional regulation of gene expression in transgenic mice. Nat Med 13, 498.

 

Cohen, D., Tian, Y., and Musch, A. (2007). Par1b Promotes Hepatic-type Lumen Polarity in Madin Darby Canine Kidney Cells via Myosin II- and E-Cadherin-dependent Signaling. Mol Biol Cell 18, 2203-2215.

 

Coleman, M. L., McDonough, M. A., Hewitson, K. S., Coles, C., Mecinovic, J., Edelmann, M., Cook, K. M., Cockman, M. E., Lancaster, D. E., Kessler, B. M., et al. (2007). Asparaginyl Hydroxylation of the Notch Ankyrin Repeat Domain by Factor Inhibiting Hypoxia-inducible Factor. Journal of Biological Chemistry 282, 24027.

 

Conlin, L. K., and Nelson, H. C. M. (2007). The Natural Osmolyte Trehalose Is a Positive Regulator of the Heat-Induced Activity of Yeast Heat Shock Transcription Factor. Mol Cell Biol 27, 1505-1515.

 

Conrad, N. K., Shu, M.-D., Uyhazi, K. E., and Steitz, J. A. (2007). Mutational analysis of a viral RNA element that counteracts rapid RNA decay by interaction with the polyadenylate tail. Proceedings of the National Academy of Sciences 104, 10412-10417.

 

Cougot, D., Wu, Y., Cairo, S., Caramel, J., Renard, C.-A., Levy, L., Buendia, M. A., and Neuveut, C. (2007). The Hepatitis B Virus X Protein Functionally Interacts with CREB-binding Protein/p300 in the Regulation of CREB-mediated Transcription. Journal of Biological Chemistry 282, 4277.

 

Cowling, V. H., and Cole, M. D. (2007). The Myc Transactivation Domain Promotes Global Phosphorylation of the RNA Polymerase II Carboxy-Terminal Domain Independently of Direct DNA Binding. Mol Cell Biol 27, 2059-2073.

 

Cowling, V. H., D'Cruz, C. M., Chodosh, L. A., and Cole, M. D. (2007). c-Myc Transforms Human Mammary Epithelial Cells through Repression of the Wnt Inhibitors DKK1 and SFRP1. Molecular and Cellular Biology 27, 5135.

 

Crepaldi, T., Bersani, F., Scuoppo, C., Accornero, P., Prunotto, C., Taulli, R., Forni, P. E., Leo, C., Chiarle, R., Griffiths, J., et al. (2007). Conditional Activation of MET in Differentiated Skeletal Muscle Induces Atrophy. Journal of Biological Chemistry 282, 6812.

 

Crighton, D., O'Prey, J., Bell, H. S., and Ryan, K. M. (2007). p73 regulates DRAM-independent autophagy that does not contribute to programmed cell death. Cell Death Differ 14, 1071.

 

Curinga, G. M., Snow, D. M., Mashburn, C., Kohler, K., Thobaben, R., Caggiano, A. O., and Smith, G. M. (2007). Mammalian-produced chondroitinase AC mitigates axon inhibition by chondroitin sulfate proteoglycans. Journal of Neurochemistry 102, 275-288.

 

Dacwag, C. S., Ohkawa, Y., Pal, S., Sif, S., and Imbalzano, A. N. (2007). The Protein Arginine Methyltransferase Prmt5 Is Required for Myogenesis because It Facilitates ATP-Dependent Chromatin Remodeling. Mol Cell Biol 27, 384-394.

 

D'Alessio, A., Cerchia, L., Amelio, I., Incoronato, M., Condorelli, G., and de Franciscis, V. (2007). Shp2 in PC12 cells: NGF versus EGF signalling. Cellular Signalling 19, 1193.

 

Das, A. T., Harwig, A., Vrolijk, M. M., and Berkhout, B. (2007). The TAR Hairpin of Human Immunodeficiency Virus Type 1 Can Be Deleted When Not Required for Tat-Mediated Activation of Transcription. Journal of Virology 81, 7742.

 

Das, A. T., Klaver, B., Harwig, A., Vink, M., Ooms, M., Centlivre, M., and Berkhout, B. (2007). Construction of a Doxycycline-Dependent Simian Immunodeficiency Virus Reveals a Nontranscriptional Function of Tat in Viral Replication. Journal of Virology 81, 11159.

 

David Greber, M. F. (2007). Multi-gene engineering: Simultaneous expression and knockdown of six genes off a single platform. Biotechnology and Bioengineering 96, 821-834.

 

Dawson, S. C., Sagolla, M. S., Mancuso, J. J., Woessner, D. J., House, S. A., Fritz-Laylin, L., and Cande, W. Z. (2007). Kinesin-13 Regulates Flagellar, Interphase, and Mitotic Microtubule Dynamics in Giardia intestinalis. Eukaryotic Cell 6, 2354.

 

De Falco, V., Castellone, M. D., De Vita, G., Cirafici, A. M., Hershman, J. M., Guerrero, C., Fusco, A., Melillo, R. M., and Santoro, M. (2007). RET/Papillary Thyroid Carcinoma Oncogenic Signaling through the Rap1 Small GTPase. Cancer Res 67, 381-390.

 

de la Fuente, M. A., Sasahara, Y., Calamito, M., Anton, I. M., Elkhal, A., Gallego, M. D., Suresh, K., Siminovitch, K., Ochs, H. D., Anderson, K. C., et al. (2007). WIP is a chaperone for Wiskott-Aldrich syndrome protein (WASP). PNAS 104, 926-931.

 

de las Mercedes Segura, M., Kamen, A., Lavoie, M.-C., and Garnier, A. (2007). Exploiting heparin-binding properties of MoMLV-based retroviral vectors for affinity chromatography. Journal of Chromatography B 846, 124.

 

Dechat, T., Shimi, T., Adam, S. A., Rusinol, A. E., Andres, D. A., Spielmann, H. P., Sinensky, M. S., and Goldman, R. D. (2007). Alterations in mitosis and cell cycle progression caused by a mutant lamin A known to accelerate human aging. PNAS 104, 4955-4960.

 

Deeble, P. D., Cox, M. E., Frierson, H. F., Jr., Sikes, R. A., Palmer, J. B., Davidson, R. J., Casarez, E. V., Amorino, G. P., and Parsons, S. J. (2007). Androgen-Independent Growth and Tumorigenesis of Prostate Cancer Cells Are Enhanced by the Presence of PKA-Differentiated Neuroendocrine Cells. Cancer Res 67, 3663-3672.

 

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Jiang, X., Zhao, Y., Smith, C., Gasparetto, M., Turhan, A., Eaves, A., and Eaves, C. (2007). Chronic myeloid leukemia stem cells possess multiple unique features of resistance to BCR-ABL targeted therapies. Leukemia 21, 926.

 

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Jones, R. A., Campbell, C. I., Gunther, E. J., Chodosh, L. A., Petrik, J. J., Khokha, R., and Moorehead, R. A. (2007). Transgenic overexpression of IGF-IR disrupts mammary ductal morphogenesis and induces tumor formation. Oncogene 26, 1636.

 

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Kamnasaran, D., Qian, B., Hawkins, C., Stanford, W. L., and Guha, A. (2007). From the Cover: GATA6 is an astrocytoma tumor suppressor gene identified by gene trapping of mouse glioma model. Proceedings of the National Academy of Sciences 104, 8053-8058.

 

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Kamsteeg, E.-J., Duffield, A. S., Konings, I. B. M., Spencer, J., Pagel, P., Deen, P. M. T., and Caplan, M. J. (2007). MAL decreases the internalization of the aquaporin-2 water channel. Proceedings of the National Academy of Sciences 104, 16696-16701.

 

Kang, H.-R., Cho, S. J., Lee, C. G., Homer, R. J., and Elias, J. A. (2007). Transforming Growth Factor (TGF)-beta1 Stimulates Pulmonary Fibrosis and Inflammation via a Bax-dependent, Bid-activated Pathway That Involves Matrix Metalloproteinase-12. Journal of Biological Chemistry 282, 7723.

 

Kang, H.-R., Lee, C. G., Homer, R. J., and Elias, J. A. (2007). Semaphorin 7A plays a critical role in TGF-{beta}1-induced pulmonary fibrosis. J Exp Med 204, 1083-1093.

 

Kao, G. D., Jiang, Z., Fernandes, A. M., Gupta, A. K., and Maity, A. (2007). Inhibition of Phosphatidylinositol-3-OH Kinase/Akt Signaling Impairs DNA Repair in Glioblastoma Cells following Ionizing Radiation. Journal of Biological Chemistry 282, 21206.

 

Kar, A., Bhattacharya, B., and Roy, P. (2007). Bluetongue virus RNA binding protein NS2 is a modulator of viral replication and assembly. BMC Molecular Biology 8, 4.

 

Karnik, S. K., Chen, H., McLean, G. W., Heit, J. J., Gu, X., Zhang, A. Y., Fontaine, M., Yen, M. H., and Kim, S. K. (2007). Menin Controls Growth of Pancreatic {beta}-Cells in Pregnant Mice and Promotes Gestational Diabetes Mellitus. Science 318, 806.

 

Karni-Schmidt, O., Friedler, A., Zupnick, A., McKinney, K., Mattia, M., Beckerman, R., Bouvet, P., Sheetz, M., Fersht, A., and Prives, C. (2007). Energy-dependent nucleolar localization of p53 in vitro requires two discrete regions within the p53 carboxyl terminus. Oncogene 26, 3878.

 

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Kasman, L., Lu, P., and Voelkel-Johnson, C. (2007). The histone deacetylase inhibitors depsipeptide and MS-275, enhance TRAIL gene therapy of LNCaP prostate cancer cells without adverse effects in normal prostate epithelial cells. Cancer Gene Ther 14, 327.

 

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Katsantoni, E., Anghelescu, N., Rottier, R., Moerland, M., Antoniou, M., de Crom, R., Grosveld, F., and Strouboulis, J. (2007). Ubiquitous expression of the rtTA2S-M2 inducible system in transgenic mice driven by the human hnRNPA2B1/CBX3 CpG island. BMC Developmental Biology 7, 108.

 

Keller, D. M., McWeeney, S., Arsenlis, A., Drouin, J., Wright, C. V. E., Wang, H., Wollheim, C. B., White, P., Kaestner, K. H., and Goodman, R. H. (2007). Characterization of Pancreatic Transcription Factor Pdx-1 Binding Sites Using Promoter Microarray and Serial Analysis of Chromatin Occupancy. Journal of Biological Chemistry 282, 32084.

 

Kharas, M. G., Yusuf, I., Scarfone, V. M., Yang, V. W., Segre, J. A., Huettner, C. S., and Fruman, D. A. (2007). KLF4 suppresses transformation of pre-B cells by ABL oncogenes. Blood 109, 747-755.

 

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Kim, J., Temple, K. A., Jones, S. A., Meredith, K. N., Basko, J. L., and Brady, M. J. (2007). Differential Modulation of 3T3-L1 Adipogenesis Mediated by 11beta-Hydroxysteroid Dehydrogenase-1 Levels. Journal of Biological Chemistry 282, 11038.

 

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Kim, N., Abdulovic, A. L., Gealy, R., Lippert, M. J., and Jinks-Robertson, S. (2007). Transcription-associated mutagenesis in yeast is directly proportional to the level of gene expression and influenced by the direction of DNA replication. DNA Repair 6, 1285.

 

Kim, S., Huang, L.-W., Snow, K. J., Ablamunits, V., Hasham, M. G., Young, T. H., Paulk, A. C., Richardson, J. E., Affourtit, J. P., Shalom-Barak, T., et al. (2007). A mouse model of conditional lipodystrophy. Proceedings of the National Academy of Sciences 104, 16627-16632.

 

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Kim, W.-I., Wiesner, S. M., and Largaespada, D. A. (2007). Vav promoter-tTA conditional transgene expression system for hematopoietic cells drives high level expression in developing B and T cells. Experimental Hematology 35, 1231.

 

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Kittappa, R., Chang, W. W., Awatramani, R. B., and McKay, R. D. G. (2007). The foxa2 Gene Controls the Birth and Spontaneous Degeneration of Dopamine Neurons in Old Age. PLoS Biology 5, e325.

 

Kitteringham, N. R., Palmer, L., Owen, A., Lian, L.-Y., Jenkins, R., Dowdall, S., Gilmore, I., Park, B. K., and Goldring, C. E. (2007). Detection and biochemical characterisation of a novel polymorphism in the human GSTP1 gene. Biochimica et Biophysica Acta (BBA) - General Subjects 1770, 1240.

 

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Klein-Scory, S., Zapatka, M., Eilert-Micus, C., Hoppe, S., Schwarz, E., Schmiegel, W., Hahn, S., and Schwarte-Waldhoff, I. (2007). High-level inducible Smad4-reexpression in the cervical cancer cell line C4-II is associated with a gene expression profile that predicts a preferential role of Smad4 in extracellular matrix composition. BMC Cancer 7, 209.

 

Klokk, T. I., Kilander, A., Xi, Z., Waehre, H., Risberg, B., Danielsen, H. E., and Saatcioglu, F. (2007). Kallikrein 4 Is a Proliferative Factor that Is Overexpressed in Prostate Cancer. Cancer Res %R 101158/0008-5472CAN-06-4728 67, 5221-5230.

 

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Knappskog, S., Ravneberg, H., Gjerdrum, C., Troe, C., Stern, B., and Pryme, I. F. (2007). The level of synthesis and secretion of Gaussia princeps luciferase in transfected CHO cells is heavily dependent on the choice of signal peptide. Journal of Biotechnology 128, 705.

 

Knostman, K. A. B., Venkateswaran, A., Zimmerman, B., Capen, C. C., and Jhiang, S. M. (2007). Creation and Characterization of a Doxycycline-Inducible Mouse Model of Thyroid-Targeted RET/PTC1 Oncogene and Luciferase Reporter Gene Coexpression. Thyroid 17, 1181-1188.

 

Kobielak, K., Stokes, N., de la Cruz, J., Polak, L., and Fuchs, E. (2007). Loss of a quiescent niche but not follicle stem cells in the absence of bone morphogenetic protein signaling. Proceedings of the National Academy of Sciences 104, 10063-10068.

 

Kohlhaas, S. L., Craxton, A., Sun, X.-M., Pinkoski, M. J., and Cohen, G. M. (2007). Receptor-mediated Endocytosis Is Not Required for Tumor Necrosis Factor-related Apoptosis-inducing Ligand (TRAIL)-induced Apoptosis. Journal of Biological Chemistry 282, 12831.

 

Komatsu, S., and Ikebe, M. (2007). The Phosphorylation of Myosin II at the Ser1 and Ser2 Is Critical for Normal Platelet-derived Growth Factor induced Reorganization of Myosin Filaments. Mol Biol Cell 18, 5081-5090.

 

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Kopnin, P. B., Agapova, L. S., Kopnin, B. P., and Chumakov, P. M. (2007). Repression of Sestrin Family Genes Contributes to Oncogenic Ras-Induced Reactive Oxygen Species Up-regulation and Genetic Instability. Cancer Res %R 101158/0008-5472CAN-06-2466 67, 4671-4678.

 

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Kornmann, B., Schaad, O., Bujard, H., Takahashi, J. S., and Schibler, U. (2007). System-Driven and Oscillator-Dependent Circadian Transcription in Mice with a Conditionally Active Liver Clock. PLoS Biology 5, e34.

 

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Kumar, P., Ambasta, R. K., Veereshwarayya, V., Rosen, K. M., Kosik, K. S., Band, H., Mestril, R., Patterson, C., and Querfurth, H. W. (2007). CHIP and HSPs interact with {beta}-APP in a proteasome-dependent manner and influence A{beta} metabolism. Hum Mol Genet 16, 848-864.

 

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Kurosu, T., Tsuji, K., Kida, A., Koyama, T., Yamamoto, M., and Miura, O. (2007). Rottlerin synergistically enhances imatinib-induced apoptosis of BCR//ABL-expressing cells through its mitochondrial uncoupling effect independent of protein kinase C-[delta]. Oncogene 26, 2975.

 

Kutcher, M. E., Kolyada, A. Y., Surks, H. K., and Herman, I. M. (2007). Pericyte Rho GTPase Mediates Both Pericyte Contractile Phenotype and Capillary Endothelial Growth State. American Journal of Pathology 171, 693.

 

Kwon, M.-S., Hori, T., Okada, M., and Fukagawa, T. (2007). CENP-C Is Involved in Chromosome Segregation, Mitotic Checkpoint Function, and Kinetochore Assembly. Mol Biol Cell 18, 2155-2168.

 

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Lai, P., Chi, T.-Y., and Chen, G. (2007). Different levels of p53 induced either apoptosis or cell cycle arrest in a doxycycline-regulated hepatocellular carcinoma cell line in vitro. Apoptosis 12, 387.

 

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Lamartina, S., Cimino, M., Roscilli, G., Dammassa, E., Lazzaro, D., Rota, R., Ciliberto, G., and Toniatti, C. (2007). Helper-dependent adenovirus for the gene therapy of proliferative retinopathies: stable gene transfer, regulated gene expression and therapeutic efficacy. J Gene Med 9, 862-874.

 

Lang, T., Dalal, S., Chikova, A., DiMaio, D., and Sweasy, J. B. (2007). The E295K DNA Polymerase Beta Gastric Cancer-Associated Variant Interferes with Base Excision Repair and Induces Cellular Transformation. Molecular and Cellular Biology 27, 5587.

 

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Lee, A. Y.-L., Liu, E., and Wu, X. (2007). The Mre11/Rad50/Nbs1 Complex Plays an Important Role in the Prevention of DNA Rereplication in Mammalian Cells. Journal of Biological Chemistry 282, 32243.

 

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Lee, H.-S., and Tomarev, S. I. (2007). Optimedin induces expression of N-cadherin and stimulates aggregation of NGF-stimulated PC12 cells. Experimental Cell Research 313, 98.

 

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Lee, P.-T., Liao, P.-C., Chang, W.-C., and Tseng, J. T. (2007). Epidermal Growth Factor Increases the Interaction between Nucleolin and Heterogeneous Nuclear Ribonucleoprotein K/Poly(C) Binding Protein 1 Complex to Regulate the Gastrin mRNA Turnover. Mol Biol Cell 18, 5004-5013.

 

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Leeb, M., and Wutz, A. (2007). Ring1B is crucial for the regulation of developmental control genes and PRC1 proteins but not X inactivation in embryonic cells. The Journal of Cell Biology 178, 219.

 

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Lemaire, R., Bayle, J., Mecham, R. P., and Lafyatis, R. (2007). Microfibril-associated MAGP-2 Stimulates Elastic Fiber Assembly. Journal of Biological Chemistry 282, 800.

 

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Li, B., Smith, C. C., Laing, J. M., Gober, M. D., Liu, L., and Aurelian, L. (2007). Overload of the heat-shock protein H11//HspB8 triggers melanoma cell apoptosis through activation of transforming growth factor-[beta]-activated kinase 1. Oncogene 26, 3521.

 

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Li, G., and Leff, T. (2007). Altered Promoter Recycling Rates Contribute to Dominant-Negative Activity of Human Peroxisome Proliferator-Activated Receptor-{gamma} Mutations Associated with Diabetes. Molecular Endocrinology 21, 857.

 

Li, H. G., Wang, Q., Li, H. M., Kumar, S., Parker, C., Slevin, M., and Kumar, P. (2007). PAX3 and PAX3-FKHR promote rhabdomyosarcoma cell survival through downregulation of PTEN. Cancer Letters 253, 215.

 

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Li, W., Hardwick, M. J., Rosenthal, D., Culty, M., and Papadopoulos, V. (2007). Peripheral-type benzodiazepine receptor overexpression and knockdown in human breast cancer cells indicate its prominent role in tumor cell proliferation. Biochemical Pharmacology 73, 491.

 

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