Leadership In Controlled Gene Expression

2001

Adimoolam, S., Lin, C. X., and Ford, J. M. (2001). The p53-regulated Cyclin-dependent Kinase Inhibitor, p21 (cip1, waf1, sdi1), Is Not Required for Global Genomic and Transcription-coupled Nucleotide Excision Repair of UV-induced DNA Photoproducts. J Biol Chem 276, 25813-25229.

 

Agarwal, M. L., Ramana, C. V., Hamilton, M., Taylor, W. R., DePrimo, S. E., Bean, L. J., Agarwal, A., Agarwal, M. K., Wolfman, A., and Stark, G. R. (2001). Regulation of p53 expression by the RAS-MAP kinase pathway. Oncogene 20, 2527-2536.

 

Aigner, A., Juhl, H., Malerczyk, C., Tkybusch, A., Benz, C. C., and Czubayko, F. (2001). Expression of a truncated 100 kDa HER2 splice variant acts as an endogenous inhibitor of tumour cell proliferation. Oncogene 20, 2101-2111.

 

Akagi, K., Kanai, M., Saya, H., Kozu, T., and Berns, A. (2001). A novel tetracycline-dependent transactivator with E2F4 transcriptional activation domain. Nucleic Acids Res 29, E23.

 

Akari, H., Bour, S., Kao, S., Adachi, A., and Strebel, K. (2001). The Human Immunodeficiency Virus Type 1 Accessory Protein Vpu Induces Apoptosis by Suppressing the Nuclear Factor {kappa}B-dependent Expression of Antiapoptotic Factors. J Exp Med 194, 1299-1276.

 

Amann, J. M., Nip, J., Strom, D. K., Lutterbach, B., Harada, H., Lenny, N., Downing, J. R., Meyers, S., and Hiebert, S. W. (2001). ETO, a Target of t(8;21) in Acute Leukemia, Makes Distinct Contacts with Multiple Histone Deacetylases and Binds mSin3A through Its Oligomerization Domain. Mol Cell Biol 21, 6470-5590.

 

Anand, M., Rush, J. S., Ray, S., Doucey, M., Weik, J., Ware, F. E., Hofsteenge, J., Waechter, C. J., and Lehrman, M. A. (2001). Requirement of the lec35 gene for all known classes of monosaccharide-p-dolichol-dependent glycosyltransferase reactions in mammals. Mol Biol Cell 12, 487-501.

 

Ando, T., Kawabe, T., Ohara, H., Ducommun, B., Itoh, M., and Okamoto, T. (2001). Involvement of the Interaction between p21 and Proliferating Cell Nuclear Antigen for the Maintenance of G2/M Arrest after DNA Damage. J Biol Chem 276, 42971-44449.

 

Ang, E., Chen, J., Zagouras, P., Magna, H., Holland, J., Schaeffer, E., and Nestler, E. J. (2001). Induction of nuclear factor-kappaB in nucleus accumbens by chronic cocaine administration. J Neurochem 79, 221-224.

 

Aplin, A. E., Stewart, S. A., Assoian, R. K., and Juliano, R. L. (2001). Integrin-mediated adhesion Regulates ERK Nuclear Translocation and Phosphorylation of Elk-1. J Cell Biol 153, 273-148.

 

Arai, A., Nosaka, Y., Kanda, E., Yamamoto, K., Miyasaka, N., and Miura, O. (2001). Rap1 Is Activated by Erythropoietin or Interleukin-3 and Is Involved in Regulation of beta 1 Integrin-mediated Hematopoietic Cell Adhesion. J Biol Chem 276, 10453-16634.

 

Arima, N., Kao, C.-Y., Licht, T., Padmanabhan, R., Sasaguri, Y., and Padmanabhan, R. (2001). Modulation of Cell Growth by the Hepatitis C Virus Nonstructural Protein NS5A. J Biol Chem 276, 12675-16634.

 

Arlt, A., Grobe, O., Sieke, A., Kruse, M. L., Folsch, U. R., Schmidt, W. E., and Schafer, H. (2001). Expression of the NF-kappa B target gene IEX-1 (p22/PRG1) does not prevent cell death but instead triggers apoptosis in Hela cells. Oncogene 20, 69-76.

 

Arrabal, S., Touchard, M., Mouthon, F., Klonjkowski, B., Deslys, J. P., Dormont, D., and Eloit, M. (2001). Nervous and nonnervous cell transduction by recombinant adenoviruses that inducibly express the human prp. Biochem Biophys Res Commun 285, 623-632.

 

Auguste, P., Gursel, D. B., Lemiere, S., Reimers, D., Cuevas, P., Carceller, F., Di Santo, J. P., and Bikfalvi, A. (2001). Inhibition of Fibroblast Growth Factor/Fibroblast Growth Factor Receptor Activity in Glioma Cells Impedes Tumor Growth by Both Angiogenesis-dependent and -independent Mechanisms. Cancer Res 61, 1717-1726.

 

Aurisicchio, L., Bujard, H., Hillen, W., Cortese, R., Ciliberto, G., La Monica, N., and Palombo, F. (2001). Regulated and prolonged expression of mIFN(alpha) in immunocompetent mice mediated by a helper-dependent adenovirus vector. Gene Ther 8, 1817-1825.

 

Ausserlechner, M. J., Obexer, P., Wiegers, G. J., Hartmann, B. L., Geley, S., and Kofler, R. (2001). The Cell Cycle Inhibitor p16INK4A Sensitizes Lymphoblastic Leukemia Cells to Apoptosis by Physiologic Glucocorticoid Levels. J Biol Chem 276, 10984-16634.

 

Bachl, J., Carlson, C., Gray-Schopfer, V., Dessing, M., and Olsson, C. (2001). Increased Transcription Levels Induce Higher Mutation Rates in a Hypermutating Cell Line. J Immunol 166, 5051-7032.

 

Bader, A. G., Schneider, M. L., Bister, K., and Hartl, M. (2001). TOJ3, a target of the v-Jun transcription factor, encodes a protein with transforming activity related to human microspherule protein 1 (MCRS1). Oncogene 20, 7524-7535.

 

Baetu, T. M., Kwon, H., Sharma, S., Grandvaux, N., and Hiscott, J. (2001). Disruption of NF-{kappa}B Signaling Reveals a Novel Role for NF-{kappa}B in the Regulation of TNF-Related Apoptosis-Inducing Ligand Expression. J Immunol 167, 3164-7110.

 

Baker, A. J., Redfern, C. H., Harwood, M. D., Simpson, P. C., and Conklin, B. R. (2001). Abnormal contraction caused by expression of Gi-coupled receptor in transgenic model of dilated cardiomyopathy. Am J Physiol Heart Circ Physiol 280, H1653-1089.

 

Baker, J. E., Majeti, R., Tangye, S. G., and Weiss, A. (2001). Protein Tyrosine Phosphatase CD148-Mediated Inhibition of T-Cell Receptor Signal Transduction Is Associated with Reduced LAT and Phospholipase C{gamma}1 Phosphorylation. Mol Cell Biol 21, 2393-4828.

 

Ballas, N., Battaglioli, E., Atouf, F., Andres, M. E., Chenoweth, J., Anderson, M. E., Burger, C., Moniwa, M., Davie, J. R., Bowers, W. J., et al. (2001). Regulation of neuronal traits by a novel transcriptional complex. Neuron 31, 353-365.

 

Bao, S., Tibbetts, R. S., Brumbaugh, K. M., Fang, Y., Richardson, D. A., Ali, A., Chen, S. M., Abraham, R. T., and Wang, X. F. (2001). ATR/ATM-mediated phosphorylation of human Rad17 is required for genotoxic stress responses. Nature 411, 969-974.

 

Bardelli, A., Cahill, D. P., Lederer, G., Speicher, M. R., Kinzler, K. W., Vogelstein, B., and Lengauer, C. (2001). From the Cover: Carcinogen-specific induction of genetic instability. PNAS 98, 5770-6347.

 

Barker, N., Hurlstone, A., Musisi, H., Miles, A., Bienz, M., and Clevers, H. (2001). The chromatin remodelling factor Brg-1 interacts with beta-catenin to promote target gene activation. Embo J 20, 4935-4943.

 

Bartke, T., Siegmund, D., Peters, N., Reichwein, M., Henkler, F., Scheurich, P., and Wajant, H. (2001). p53 upregulates cFLIP, inhibits transcription of NF-kappaB-regulated genes and induces caspase-8-independent cell death in DLD-1 cells. Oncogene 20, 571-580.

 

Bean, L. J., and Stark, G. R. (2001). Phosphorylation of serines 15 and 37 is necessary for efficient accumulation of p53 following irradiation with UV. Oncogene 20, 1076-1084.

 

Becskei, A., Seraphin, B., and Serrano, L. (2001). Positive feedback in eukaryotic gene networks: cell differentiation by graded to binary response conversion. EMBO J 20, 2528-2539.

 

Bennett, E. M., Lin, S. X., Towler, M. C., Maxfield, F. R., and Brodsky, F. M. (2001). Clathrin hub expression affects early endosome distribution with minimal impact on receptor sorting and recycling. Mol Biol Cell 12, 2790-2799.

 

Berkovich, I., and Efrat, S. (2001). Inducible and reversible beta-cell autoimmunity and hyperplasia in transgenic mice expressing a conditional oncogene. Diabetes 50, 2260-2267.

 

Bi, Y. M., Rothstein, S. J., and Wildeman, A. G. (2001). A novel strategy for regulated expression of a cytotoxic gene. Gene 279, 175-179.

 

Bilger, M., Heger, S., Brann, D. W., Paredes, A., and Ojeda, S. R. (2001). A Conditional Tetracycline-Regulated Increase in Gamma Amino Butyric Acid Production near Luteinizing Hormone-Releasing Hormone Nerve Terminals Disrupts Estrous Cyclicity in the Rat. Endocrinology 142, 2102-2114.

 

Biola, A., Lefebvre, P., Perrin-Wolff, M., Sturm, M., Bertoglio, J., and Pallardy, M. (2001). Interleukin-2 Inhibits Glucocorticoid Receptor Transcriptional Activity through a Mechanism Involving STAT5 (Signal Transducer and Activator of Transcription 5) but Not AP-1. Mol Endocrinol 15, 1062-1076.

 

Bjornsson, J. M., Andersson, E., Lundstrom, P., Larsson, N., Xu, X., Repetowska, E., Humphries, R. K., and Karlsson, S. (2001). Proliferation of primitive myeloid progenitors can be reversibly induced by HOXA10. Blood 98, 3301-3308.

 

Blesch, A., Conner, J. M., and Tuszynski, M. H. (2001). Modulation of neuronal survival and axonal growth in vivo by tetracycline-regulated neurotrophin expression. Gene Ther 8, 954-960.

 

Bohner, S., and Gatz, C. (2001). Characterisation of novel target promoters for the dexamethasone-inducible/tetracycline-repressible regulator TGV using luciferase and isopentenyl transferase as sensitive reporter genes. Molecular and General Genetics 264, 860-870.

 

Bondurand, N., Girard, M., Pingault, V., Lemort, N., Dubourg, O., and Goossens, M. (2001). Human Connexin 32, a gap junction protein altered in the X-linked form of Charcot-Marie-Tooth disease, is directly regulated by the transcription factor SOX10. Hum Mol Genet 10, 2783-2795.

 

Boon, K., Caron, H. N., van Asperen, R., Valentijn, L., Hermus, M.-C., van Sluis, P., Roobeek, I., Weis, I., Voute, P. A., Schwab, M., and Versteeg, R. (2001). N-myc enhances the expression of a large set of genes functioning in ribosome biogenesis and protein synthesis. EMBO J 20, 1383-1339.

 

Bottazzi, M. E., Buzzai, M., Zhu, X., Desdouets, C., Brechot, C., and Assoian, R. K. (2001). Distinct Effects of Mitogens and the Actin Cytoskeleton on CREB and Pocket Protein Phosphorylation Control the Extent and Timing of Cyclin A Promoter Activity. Mol Cell Biol 21, 7607-5590.

 

Boudreau, M. D., Sohn, K. H., Rhee, S. H., Lee, S. W., Hunt, J. D., and Hwang, D. H. (2001). Suppression of Tumor Cell Growth Both in Nude Mice and in Culture by n-3 Polyunsaturated Fatty Acids: Mediation through Cyclooxygenase-independent Pathways. Cancer Res 61, 1386-1726.

 

Bour, S., Perrin, C., Akari, H., and Strebel, K. (2001). The Human Immunodeficiency Virus Type 1 Vpu Protein Inhibits NF-kappa B Activation by Interfering with beta TrCP-mediated Degradation of Ikappa B. J Biol Chem 276, 15920-16634.

 

Bradbury, C. M., Markovina, S., Wei, S. J., Rene, L. M., Zoberi, I., Horikoshi, N., and Gius, D. (2001). Indomethacin-induced Radiosensitization and Inhibition of Ionizing Radiation-induced NF-{kappa}B Activation in HeLa Cells Occur via a Mechanism Involving p38 MAP Kinase. Cancer Res 61, 7689-5651.

 

Britsch, S., Goerich, D. E., Riethmacher, D., Peirano, R. I., Rossner, M., Nave, K. A., Birchmeier, C., and Wegner, M. (2001). The transcription factor Sox10 is a key regulator of peripheral glial development. Genes Dev 15, 66-78.

 

Buckley, A. F., Kuo, C. T., and Leiden, J. M. (2001). Transcription factor LKLF is sufficient to program T cell quiescence via a c-Myc--dependent pathway. Nat Immunol 2, 698-704.

 

Bulotta, S., Barsacchi, R., Rotiroti, D., Borgese, N., and Clementi, E. (2001). Activation of the Endothelial Nitric-oxide Synthase by Tumor Necrosis Factor-alpha . A NOVEL FEEDBACK MECHANISM REGULATING CELL DEATH. J Biol Chem 276, 6529-16634.

 

Burel, S. A., Harakawa, N., Zhou, L., Pabst, T., Tenen, D. G., and Zhang, D.-E. (2001). Dichotomy of AML1-ETO Functions: Growth Arrest versus Block of Differentiation. Mol Cell Biol 21, 5577-5590.

 

Cacalano, N. A., Sanden, D., and Johnston, J. A. (2001). Tyrosine-phosphorylated SOCS-3 inhibits STAT activation but binds to p120 RasGAP and activates Ras. Nat Cell Biol 3, 460-465.

 

Canete-Soler, R., Wu, J., Zhai, J., Shamim, M., and Schlaepfer, W. W. (2001). p190RhoGEF Binds to a Destabilizing Element in the 3' Untranslated Region of Light Neurofilament Subunit mRNA and Alters the Stability of the Transcript. J Biol Chem 276, 32046-32190.

 

Cebrian, C., Areste, C., Nicolas, A., Olive, P., Carceller, A., Piulats, J., and Meseguer, A. (2001). Kidney Androgen-regulated Protein Interacts with Cyclophilin B and Reduces Cyclosporine A-mediated Toxicity in Proximal Tubule Cells. J Biol Chem 276, 29410-25229.

 

Ceccarelli, E., and Mann, C. (2001). A Cdc28 Mutant Uncouples G1 Cyclin Phosphorylation and Ubiquitination from G1 Cyclin Proteolysis. J Biol Chem 276, 41725-44449.

 

Ceresa, B. P., Lotscher, M., and Schmid, S. L. (2001). Receptor and Membrane Recycling Can Occur with Unaltered Efficiency Despite Dramatic Rab5(Q79L)-induced Changes in Endosome Geometry. J Biol Chem 276, 9649-16634.

 

Chai, Z., Sarcevic, B., Mawson, A., and Toh, B.-H. (2001). SET-related Cell Division Autoantigen-1 (CDA1) Arrests Cell Growth. J Biol Chem 276, 33665-32190.

 

Chattopadhyay, A., Chiang, C. W., and Yang, E. (2001). BAD/BCL-(xL) heterodimerization leads to bypass of G0/G1 arrest. Oncogene 20, 4507-4518.

 

Chen, W., Yu, Y.-L., Lee, S.-F., Chiang, Y.-J., Chao, J.-R., Huang, J.-H., Chiong, J.-H., Huang, C.-J., Lai, M.-Z., Yang-Yen, H.-F., and Yen, J. J.-Y. (2001). CREB Is One Component of the Binding Complex of the Ces-2/E2A-HLF Binding Element and Is an Integral Part of the Interleukin-3 Survival Signal. Mol Cell Biol 21, 4636-4828.

 

Chen, X., Zheng, Y., Zhu, J., Jiang, J., and Wang, J. (2001). p73 is transcriptionally regulated by DNA damage, p53, and p73. Oncogene 20, 769-774.

 

Cho, J. W., Baek, W. K., Yang, S. H., Chang, J., Sung, Y. C., and Suh, M. H. (2001). HCV core protein modulates Rb pathway through pRb down- regulation and E2F-1 up-regulation. Biochimica Et Biophysica Acta-Molecular Cell Research 1538, 59-66.

 

Christen, U., Wolfe, T., Mohrle, U., Hughes, A. C., Rodrigo, E., Green, E. A., Flavell, R. A., and von Herrath, M. G. (2001). A Dual Role for TNF-{{alpha}} in Type 1 Diabetes: Islet-Specific Expression Abrogates the Ongoing Autoimmune Process When Induced Late but Not Early During Pathogenesis. J Immunol 166, 7023-7032.

 

Citores, L., Khnykin, D., Sorensen, V., Wesche, J., Klingenberg, O., Wiedlocha, A., and Olsnes, S. (2001). Modulation of intracellular transport of acidic fibroblast growth factor by mutations in the cytoplasmic receptor domain. J Cell Sci 114, 1677-1343.

 

Clark, J. C., Tichelaar, J. W., Wert, S. E., Itoh, N., Perl, A.-K. T., Stahlman, M. T., and Whitsett, J. A. (2001). FGF-10 disrupts lung morphogenesis and causes pulmonary adenomas in vivo. Am J Physiol Lung Cell Mol Physiol 280, L705-1089.

 

Claudio, P. P., Stiegler, P., Howard, C. M., Bellan, C., Minimo, C., Tosi, G. M., Rak, J., Kovatich, A., Paola De Fazio, Micheli, P., et al. (2001). RB2/p130 Gene-enhanced Expression Down-Regulates Vascular Endothelial Growth Factor Expression and Inhibits Angiogenesis in Vivo. Cancer Res 61, 462-1726.

 

Clement, J. Q., Maiti, S., and Wilkinson, M. F. (2001). Localization and Stability of Introns Spliced from the Pem Homeobox Gene. J Biol Chem 276, 16919-16634.

 

Cohen, D., Musch, A., and Rodriguez-Boulan, E. (2001). Selective control of basolateral membrane protein polarity by cdc42. Traffic 2, 556-564.

 

Comijn, J., Berx, G., Vermassen, P., Verschueren, K., van Grunsven, L., Bruyneel, E., Mareel, M., Huylebroeck, D., and van Roy, F. (2001). The two-handed E box binding zinc finger protein SIP1 downregulates E-cadherin and induces invasion. Mol Cell 7, 1267-1278.

 

Coniglio, S. J., Jou, T.-S., and Symons, M. (2001). Rac1 Protects Epithelial Cells against Anoikis. J Biol Chem 276, 28113-25229.

 

Cottet, S., Dupraz, P., Hamburger, F., Dolci, W., Jaquet, M., and Thorens, B. (2001). SOCS-1 Protein Prevents Janus Kinase/STAT-dependent Inhibition of beta Cell Insulin Gene Transcription and Secretion in Response to Interferon-gamma J Biol Chem 276, 25862-25229.

 

Craddock, B. L., Hobbs, J., Edmead, C. E., and Welham, M. J. (2001). Phosphoinositide 3-Kinase-dependent Regulation of Interleukin-3-induced Proliferation. INVOLVEMENT OF MITOGEN-ACTIVATED PROTEIN KINASES, SHP2 AND Gab2. J Biol Chem 276, 24274-25229.

 

Criss, A., Ahlgren, D., Jou, T., McCormick, B., and Casanova, J. (2001). The GTPase Rac1 selectively regulates Salmonella invasion at the apical plasma membrane of polarized epithelial cells. J Cell Sci 114, 1331-1343.

 

D'Cruz, C. M., Gunther, E. J., Boxer, R. B., Hartman, J. L., Sintasath, L., Moody, S. E., Cox, J. D., Ha, S. I., Belka, G. K., Golant, A., et al. (2001). c-MYC induces mammary tumorigenesis by means of a preferred pathway involving spontaneous Kras2 mutations. Nat Med 7, 235-239.

 

Dai, J., Shen, R., Sumitomo, M., Goldberg, J. S., Geng, Y., Navarro, D., Xu, S., Koutcher, J. A., Garzotto, M., Powell, C. T., and Nanus, D. M. (2001). Tumor-suppressive effects of neutral endopeptidase in androgen-independent prostate cancer cells. Clin Cancer Res 7, 1370-1377.

 

Dalle, B., Henri, A., Rouyer-Fessard, P., Bettan, M., Scherman, D., Beuzard, Y., and Payen, E. (2001). Dimeric erythropoietin fusion protein with enhanced erythropoietic activity in vitro and in vivo. Blood 97, 3776-3782.

 

Damke, H., Binns, D. D., Ueda, H., Schmid, S. L., and Baba, T. (2001). Dynamin gtpase domain mutants block endocytic vesicle formation at morphologically distinct stages. Mol Biol Cell 12, 2578-2589.

 

de la Serna, I. L., Carlson, K. A., and Imbalzano, A. N. (2001). Mammalian SWI/SNF complexes promote MyoD-mediated muscle differentiation. Nat Genet 27, 187-190.

 

de la Serna, I. L., Roy, K., Carlson, K. A., and Imbalzano, A. N. (2001). MyoD Can Induce Cell Cycle Arrest but Not Muscle Differentiation in the Presence of Dominant Negative SWI/SNF Chromatin Remodeling Enzymes. J Biol Chem 276, 41486-32190.

 

Dean, J. L. E., Wait, R., Mahtani, K. R., Sully, G., Clark, A. R., and Saklatvala, J. (2001). The 3' Untranslated Region of Tumor Necrosis Factor Alpha mRNA Is a Target of the mRNA-Stabilizing Factor HuR. Mol Cell Biol 21, 721-1539.

 

Dejneka, N. S., Auricchio, A., Maguire, A. M., Ye, X., Gao, G. P., Wilson, J. M., and Bennett, J. (2001). Pharmacologically regulated gene expression in the retina following transduction with viral vectors. Gene Therapy 8, 442-446.

 

Detich, N., Ramchandani, S., and Szyf, M. (2001). A Conserved 3'-Untranslated Element Mediates Growth Regulation of DNA Methyltransferase 1 and Inhibits Its Transforming Activity. J Biol Chem 276, 24881-25229.

 

Deutsch, E., Dugray, A., AbdulKarim, B., Marangoni, E., Maggiorella, L., Vaganay, S., M'Kacher, R., Rasy, S. D., Eschwege, F., Vainchenker, W., et al. (2001). BCR-ABL down-regulates the DNA repair protein DNA-PKcs. Blood 97, 2084-2090.

 

DeWitt, A. E., Dong, J. Y., Wiley, H. S., and Lauffenburger, D. A. (2001). Quantitative analysis of the EGF receptor autocrine system reveals cryptic regulation of cell response by ligand capture. J Cell Sci 114, 2301-2343.

 

Ding, B. C., Whetstine, J. R., Witt, T. L., Schuetz, J. D., and Matherly, L. H. (2001). Repression of Human Reduced Folate Carrier Gene Expression by Wild Type p53. J Biol Chem 276, 8713-16634.

 

Dohn, M., Jiang, J., and Chen, X. (2001). Receptor tyrosine kinase EphA2 is regulated by p53-family proteins and induces apoptosis. Oncogene 20, 6503-6515.

 

Dohn, M., Zhang, S., and Chen, X. (2001). p63alpha and DeltaNp63alpha can induce cell cycle arrest and apoptosis and differentially regulate p53 target genes. Oncogene 20, 3193-3205.

 

Donald, S. P., Sun, X.-Y., Hu, C.-A. A., Yu, J., Mei, J. M., Valle, D., and Phang, J. M. (2001). Proline Oxidase, Encoded by p53-induced Gene-6, Catalyzes the Generation of Proline-dependent Reactive Oxygen Species. Cancer Res 61, 1810-3118.

 

Donze, O., Abbas-Terki, T., and Picard, D. (2001). The Hsp90 chaperone complex is both a facilitator and a repressor of the dsRNA-dependent kinase PKR. Embo J 20, 3771-3780.

 

Dor, Y., Camenisch, T. D., Itin, A., Fishman, G. I., McDonald, J. A., Carmeliet, P., and Keshet, E. (2001). A novel role for VEGF in endocardial cushion formation and its potential contribution to congenital heart defects. Development 128, 1531-1538.

 

Draviam, V. M., Orrechia, S., Lowe, M., Pardi, R., and Pines, J. (2001). The Localization of Human Cyclins B1 and B2 Determines CDK1 Substrate Specificity and Neither Enzyme Requires MEK to Disassemble the Golgi Apparatus. J Cell Biol 152, 945-148.

 

Dreijerink, K., Braga, E., Kuzmin, I., Geil, L., Duh, F.-M., Angeloni, D., Zbar, B., Lerman, M. I., Stanbridge, E. J., Minna, J. D., et al. (2001). The candidate tumor suppressor gene, RASSF1A, from human chromosome 3p21.3 is involved in kidney tumorigenesis. PNAS 98, 7504-7474.

 

Dubrez, L., Coll, J.-L., Hurbin, A., Solary, E., and Favrot, M.-C. (2001). Caffeine Sensitizes Human H358 Cell Line to p53-mediated Apoptosis by Inducing Mitochondrial Translocation and Conformational Change of BAX Protein. J Biol Chem 276, 38980-32190.

 

Dubrez, L., Coll, J. L., Hurbin, A., de Fraipont, F., Lantejoul, S., and Favrot, M. C. (2001). Cell cycle arrest is sufficient for p53-mediated tumor regression. Gene Therapy 8, 1705-1712.

 

Duchrow, M., Schmidt, M. H. H., Zingler, M., Anemuller, S., Bruch, H. P., and Broll, R. (2001). Suppression of cell division by pKi-67 antisense-RNA and recombinant protein. Cellular Physiology and Biochemistry 11, 331-338.

 

Edholm, D., Molin, M., Bajak, E., and Akusjarvi, G. (2001). Adenovirus Vector Designed for Expression of Toxic Proteins. J Virol 75, 9579-9482.

 

Egeblad, M., Mortensen, O. H., and Jaattela, M. (2001). Truncated ErbB2 receptor enhances ErbB1 signaling and induces reversible, ERK-independent loss of epithelial morphology. International Journal of Cancer 94, 185-191.

 

Eichhorn, K., and Jackson, S. P. (2001). A Role for TAF3B2 in the Repression of Human RNA Polymerase III Transcription in Nonproliferating Cells. J Biol Chem 276, 21158-21165.

 

Evert, B. O., Vogt, I. R., Kindermann, C., Ozimek, L., de Vos, R. A., Brunt, E. R., Schmitt, I., Klockgether, T., and Wullner, U. (2001). Inflammatory genes are upregulated in expanded ataxin-3-expressing cell lines and spinocerebellar ataxia type 3 brains. J Neurosci 21, 5389-5396.

 

Ezelle, H. J., Balachandran, S., Sicheri, F., Polyak, S. J., and Barber, G. N. (2001). Analyzing the mechanisms of interferon-induced apoptosis using CrmA and hepatitis C virus NS5A. Virology 281, 124-137.

 

Fajas, L., Paul, C., Vie, A., Estrach, S., Medema, R., Blanchard, J. M., Sardet, C., and Vignais, M.-L. (2001). Cyclin A Is a Mediator of p120E4F-Dependent Cell Cycle Arrest in G1. Mol Cell Biol 21, 2956-4828.

 

Falck, J., Mailand, N., Syljuasen, R. G., Bartek, J., and Lukas, J. (2001). The ATM-Chk2-Cdc25A checkpoint pathway guards against radioresistant DNA synthesis. Nature 410, 842-847.

 

Falck, J., Lukas, C., Protopopova, M., Lukas, J., Selivanova, G., and Bartek, J. (2001). Functional impact of concomitant versus alternative defects in the Chk2-p53 tumour suppressor pathway. Oncogene 20, 5503-5510.

 

Fan, X., Fan, D., Gewant, H., Royce, C. L., Nanes, M. S., and Rubin, J. (2001). Increasing membrane-bound MCSF does not enhance OPGL-driven osteoclastogenesis from marrow cells. Am J Physiol 280, E103-974.

 

Fan, S. J., Yuan, R. Q., Ma, Y. X., Meng, Q. H., Goldberg, I. D., and Rosen, E. M. (2001). Mutant BRCA1 genes antagonize phenotype of wild-type BRCA1. Oncogene 20, 8215-8235.

 

Fan, S. J., Yuan, R. Q., Ma, Y. X., Xiong, J. B., Meng, Q. H., Erdos, M., Zhao, J. N., Goldberg, I. D., Pestell, R. G., and Rosen, E. M. (2001). Disruption of BRCA1 LXCXE motif alters BRCA1 functional activity and regulation of RB family but not RB protein binding. Oncogene 20, 4827-4841.

 

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Filleur, S., Volpert, O. V., Degeorges, A., Voland, C., Reiher, F., Clezardin, P., Bouck, N., and Cabon, F. (2001). In vivo mechanisms by which tumors producing thrombospondin 1 bypass its inhibitory effects. Genes Dev 15, 1373-1382.

 

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Fisher, G. H., Wellen, S. L., Klimstra, D., Lenczowski, J. M., Tichelaar, J. W., Lizak, M. J., Whitsett, J. A., Koretsky, A., and Varmus, H. E. (2001). Induction and apoptotic regression of lung adenocarcinomas by regulation of a K-Ras transgene in the presence and absence of tumor suppressor genes. Genes Dev 15, 3249-3262.

 

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Foley, J., Dann, P., Hong, J., Cosgrove, J., Dreyer, B., Rimm, D., Dunbar, M., Philbrick, W., and Wysolmerski, J. (2001). Parathyroid hormone-related protein maintains mammary epithelial fate and triggers nipple skin differentiation during embryonic breast development. Development 128, 513-525.

 

Foster, D., Strong, R., and Morgan, W. W. (2001). A tetracycline-repressible transactivator approach suggests a shorter half-life for tyrosine hydroxylase mRNA. Brain Research Protocols 7, 137-146.

 

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Friedrichsen, B. N., Galsgaard, E. D., Nielsen, J. H., and Moldrup, A. (2001). Growth Hormone- and Prolactin-Induced Proliferation of Insulinoma Cells, INS-1, Depends on Activation of STAT5 (Signal Transducer and Activator of Transcription 5). Mol Endocrinol 15, 136-148.

 

Fu, X., Menke, J. G., Chen, Y., Zhou, G., MacNaul, K. L., Wright, S. D., Sparrow, C. P., and Lund, E. G. (2001). 27-Hydroxycholesterol Is an Endogenous Ligand for Liver X Receptor in Cholesterol-loaded Cells. J Biol Chem 276, 38378-32190.

 

Fuhrmann, G., Leisser, C., Rosenberger, G., Grusch, M., Huettenbrenner, S., Halama, T., Mosberger, I., Sasgary, S., Cerni, C., and Krupitza, G. (2001). Cdc25A phosphatase suppresses apoptosis induced by serum deprivation. Oncogene 20, 4542-4553.

 

Fukagawa, T., Mikami, Y., Nishihashi, A., Regnier, V., Haraguchi, T., Hiraoka, Y., Sugata, N., Todokoro, K., Brown, W., and Ikemura, T. (2001). CENP-H, a constitutive centromere component, is required for centromere targeting of CENP-C in vertebrate cells. Embo J 20, 4603-4617.

 

Fux, C., Moser, S., Schlatter, S., Rimann, M., Bailey, J. E., and Fussenegger, M. (2001). Streptogramin- and tetracycline-responsive dual regulated expression of p27(Kip1) sense and antisense enables positive and negative growth control of Chinese hamster ovary cells. Nucleic Acids Res 29, E19.

 

Gaiddon, C., Lokshin, M., Ahn, J., Zhang, T., and Prives, C. (2001). A Subset of Tumor-Derived Mutant Forms of p53 Down-Regulate p63 and p73 through a Direct Interaction with the p53 Core Domain. Mol Cell Biol 21, 1874-1539.

 

Gatei, M., Zhou, B.-B., Hobson, K., Scott, S., Young, D., and Khanna, K. K. (2001). Ataxia Telangiectasia Mutated (ATM) Kinase and ATM and Rad3 Related Kinase Mediate Phosphorylation of Brca1 at Distinct and Overlapping Sites. IN VIVO ASSESSMENT USING PHOSPHO-SPECIFIC ANTIBODIES. J Biol Chem 276, 17276-16634.

 

Gaubert, F., Escaffit, F., Bertrand, C., Korc, M., Pradayrol, L., Clemente, F., and Estival, A. (2001). Expression of the High Molecular Weight Fibroblast Growth Factor-2 Isoform of 210 Amino Acids Is Associated with Modulation of Protein Kinases C delta and epsilon and ERK Activation. J Biol Chem 276, 1545-2458.

 

Gaudry, C. A., Palka, H. L., Dusek, R. L., Huen, A. C., Khandekar, M. J., Hudson, L. G., and Green, K. J. (2001). Tyrosine-phosphorylated Plakoglobin Is Associated with Desmogleins but Not Desmoplakin after Epidermal Growth Factor Receptor Activation. J Biol Chem 276, 24871-25229.

 

Geley, S., Kramer, E., Gieffers, C., Gannon, J., Peters, J.-M., and Hunt, T. (2001). Anaphase-promoting Complex/Cyclosome-dependent Proteolysis of Human Cyclin A Starts at the Beginning of Mitosis and Is Not Subject to the Spindle Assembly Checkpoint. J Cell Biol 153, 137-148.

 

Giavazzi, R., Giuliani, R., Coltrini, D., Bani, M. R., Ferri, C., Sennino, B., Tosatti, M. P. M., Stoppacciaro, A., and Presta, M. (2001). Modulation of Tumor Angiogenesis by Conditional Expression of Fibroblast Growth Factor-2 Affects Early but not Established Tumors. Cancer Res 61, 309-317.

 

Gottifredi, V., Karni-Schmidt, O., Shieh, S.-Y., and Prives, C. (2001). p53 Down-Regulates CHK1 through p21 and the Retinoblastoma Protein. Mol Cell Biol 21, 1066-1539.

 

Gottlob, K., Majewski, N., Kennedy, S., Kandel, E., Robey, R. B., and Hay, N. (2001). Inhibition of early apoptotic events by Akt/PKB is dependent on the first committed step of glycolysis and mitochondrial hexokinase. Genes Dev 15, 1406-1418.

 

Gotz, J., Tolnay, M., Barmettler, R., Chen, F., Probst, A., and Nitsch, R. M. (2001). Oligodendroglial tau filament formation in transgenic mice expressing G272V tau. Eur J Neurosci 13, 2131-2140.

 

Goukassian, D., Diez-Juan, A., Asahara, T., Schratzberger, P., Silver, M., Murayama, T., Isner, J. M., and Andres, V. (2001). Overexpression of p27(Kip1) by doxycycline-regulated adenoviral vectors inhibits endothelial cell proliferation and migration and impairs angiogenesis. Faseb J 15, 1877-1885.

 

Gratton, J.-P., Morales-Ruiz, M., Kureishi, Y., Fulton, D., Walsh, K., and Sessa, W. C. (2001). Akt Down-regulation of p38 Signaling Provides a Novel Mechanism of Vascular Endothelial Growth Factor-mediated Cytoprotection in Endothelial Cells. J Biol Chem 276, 30359-32190.

 

Grigorian, M., Andresen, S., Tulchinsky, E., Kriajevska, M., Carlberg, C., Kruse, C., Cohn, M., Ambartsumian, N., Christensen, A., Selivanova, G., and Lukanidin, E. (2001). Tumor Suppressor p53 Protein Is a New Target for the Metastasis-associated Mts1/S100A4 Protein. FUNCTIONAL CONSEQUENCES OF THEIR INTERACTION. J Biol Chem 276, 22699-25229.

 

Gross, I., Bassit, B., Benezra, M., and Licht, J. D. (2001). Mammalian Sprouty Proteins Inhibit Cell Growth and Differentiation by Preventing Ras Activation. J Biol Chem 276, 46460-44449.

 

Grossman, D., Kim, P. J., Schechner, J. S., and Altieri, D. C. (2001). Inhibition of melanoma tumor growth in vivo by survivin targeting. PNAS 98, 635-4059.

 

Gu, C., and Park, S. (2001). The EphA8 Receptor Regulates Integrin Activity through p110{gamma} Phosphatidylinositol-3 Kinase in a Tyrosine Kinase Activity-Independent Manner. Mol Cell Biol 21, 4579-4828.

 

Gutmann, D. H., Haipek, C. A., Burke, S. P., Sun, C. X., Scoles, D. R., and Pulst, S. M. (2001). The NF2 interactor, hepatocyte growth factor-regulated tyrosine kinase substrate (HRS), associates with merlin in the "open" conformation and suppresses cell growth and motility. Hum Mol Genet 10, 825-834.

 

Gutmann, D. H., Hirbe, A. C., and Haipek, C. A. (2001). Functional analysis of neurofibromatosis 2 (NF2) missense mutations. Hum Mol Genet 10, 1519-1529.

 

Halford, W. P., Kemp, C. D., Isler, J. A., Davido, D. J., and Schaffer, P. A. (2001). ICP0, ICP4, or VP16 Expressed from Adenovirus Vectors Induces Reactivation of Latent Herpes Simplex Virus Type 1 in Primary Cultures of Latently Infected Trigeminal Ganglion Cells. J Virol 75, 6143-6106.

 

Han, D. C., Rodriguez, L. G., and Guan, J. L. (2001). Identification of a novel interaction between integrin beta1 and 14-3-3beta. Oncogene 20, 346-357.

 

Harada, Y., Harada, H., Downing, J. R., and Kimura, A. (2001). A hematopoietic-specific transmembrane protein, art-1, is possibly regulated by aml1. Biochem Biophys Res Commun 284, 714-722.

 

Hartl, M., Reiter, F., Bader, A. G., Castellazzi, M., and Bister, K. (2001). JAC, a direct target of oncogenic transcription factor Jun, is involved in cell transformation and tumorigenesis. PNAS 98, 13601-12965.

 

Hasan, M. T., Schonig, K., Berger, S., Graewe, W., and Bujard, H. (2001). Long-term, noninvasive imaging of regulated gene expression in living mice. Genesis 29, 116-122.

 

He, Y., Tan, S.-L., Tareen, S. U., Vijaysri, S., Langland, J. O., Jacobs, B. L., and Katze, M. G. (2001). Regulation of mRNA Translation and Cellular Signaling by Hepatitis C Virus Nonstructural Protein NS5A. J Virol 75, 5090-6106.

 

Herren, B., Garton, K. J., Coats, S., Bowen-Pope, D. F., Ross, R., and Raines, E. W. (2001). ADAM15 overexpression in NIH3T3 cells enhances cell-cell interactions. Exp Cell Res 271, 152-160.

 

Hess, J., Nielsen, P. J., Fischer, K.-D., Bujard, H., and Wirth, T. (2001). The B Lymphocyte-Specific Coactivator BOB.1/OBF.1 Is Required at Multiple Stages of B-Cell Development. Mol Cell Biol 21, 1531-1539.

 

Hess, J., Werner, A., Wirth, T., Melchers, F., Jack, H.-M., and Winkler, T. H. (2001). Induction of pre-B cell proliferation after de novo synthesis of the pre-B cell receptor. PNAS 98, 1745-4059.

 

Hirai, Y., Radisky, D., Boudreau, R., Simian, M., Stevens, M. E., Oka, Y., Takebe, K., Niwa, S., and Bissell, M. J. (2001). Epimorphin Mediates Mammary Luminal Morphogenesis through Control of C/EBP{beta}. J Cell Biol 153, 785-714.

 

Hislop, J. N., Everest, H. M., Flynn, A., Harding, T., Uney, J. B., Troskie, B. E., Millar, R. P., and McArdle, C. A. (2001). Differential Internalization of Mammalian and Non-mammalian Gonadotropin-releasing Hormone Receptors. UNCOUPLING OF DYNAMIN-DEPENDENT INTERNALIZATION FROM MITOGEN-ACTIVATED PROTEIN KINASE SIGNALING. J Biol Chem 276, 39685-32190.

 

Hofelmayr, H., Strobl, L. J., Marschall, G., Bornkamm, G. W., and Zimber-Strobl, U. (2001). Activated Notch1 Can Transiently Substitute for EBNA2 in the Maintenance of Proliferation of LMP1-Expressing Immortalized B Cells. J Virol 75, 2033-2987.

 

Hofer, T., Desbaillets, I., Hopfl, G., Gassmann, M., and Wenger, R. H. (2001). Dissecting hypoxia-dependent and hypoxia-independent steps in the HIF-1alpha activation cascade: implications for HIF-1alpha gene therapy. Faseb J 15, 2715-2717.

 

Holland, S. J., Liao, X. C., Mendenhall, M. K., Zhou, X., Pardo, J., Chu, P., Spencer, C., Fu, A., Sheng, N., Yu, P., et al. (2001). Functional Cloning of Src-like Adapter Protein-2 (SLAP-2), a Novel Inhibitor of Antigen Receptor Signaling. J Exp Med 194, 1263-1276.

 

Holtmann, H., Enninga, J., Kalble, S., Thiefes, A., Dorrie, A., Broemer, M., Winzen, R., Wilhelm, A., Ninomiya-Tsuji, J., Matsumoto, K., et al. (2001). The MAPK Kinase Kinase TAK1 Plays a Central Role in Coupling the Interleukin-1 Receptor to Both Transcriptional and RNA-targeted Mechanisms of Gene Regulation. J Biol Chem 276, 3508-16634.

 

Holzel, M., Kohlhuber, F., Schlosser, I., Holzel, D., Luscher, B., and Eick, D. (2001). Myc/Max/Mad regulate the frequency but not the duration of productive cell cycles. EMBO Rep 2, 1125-1132.

 

Hong, Y. K., Kim, D. H., Beletskii, A., Lee, C., Memili, E., and Strauss, W. M. (2001). Development of two bacterial artificial chromosome shuttle vectors for a recombination-based cloning and regulated expression of large genes in mammalian cells. Analytical Biochemistry 291, 142-148.

 

Hossain, A., and Saunders, G. F. (2001). The Human Sex-determining Gene SRY Is a Direct Target of WT1. J Biol Chem 276, 16817-16634.

 

Hsu, W., Shakya, R., and Costantini, F. (2001). Impaired mammary gland and lymphoid development caused by inducible expression of Axin in transgenic mice. J Cell Biol 155, 1055-1064.

 

Hu, B., Mitra, J., van den Heuvel, S., and Enders, G. H. (2001). S and G2 Phase Roles for Cdk2 Revealed by Inducible Expression of a Dominant-Negative Mutant in Human Cells. Mol Cell Biol 21, 2755-4828.

 

Huang, Y., Uchiyama, Y., Fujimura, T., Kanamori, H., Doi, T., Takamizawa, A., Hamakubo, T., and Kodama, T. (2001). A human hepatoma cell line expressing hepatitis C virus nonstructural proteins tightly regulated by tetracycline. Biochemical and Biophysical Research Communications 281, 732-740.

 

Huang, F., Nesterov, A., Carter, R. E., and Sorkin, A. (2001). Trafficking of yellow-fluorescent-protein-tagged mu1 subunit of clathrin adaptor AP-1 complex in living cells. Traffic 2, 345-357.

 

Hugle, T., Fehrmann, F., Bieck, E., Kohara, M., Krausslich, H. G., Rice, C. M., Blum, H. E., and Moradpour, D. (2001). Hepatitis C virus nonstructural protein 4B is an integral endoplasmic reticulum membrane protein. Virology 284, 70-81.

 

Huppertz, C., Fischer, B. M., Kim, Y.-B., Kotani, K., Vidal-Puig, A., Slieker, L. J., Sloop, K. W., Lowell, B. B., and Kahn, B. B. (2001). Uncoupling Protein 3 (UCP3) Stimulates Glucose Uptake in Muscle Cells through a Phosphoinositide 3-Kinase-dependent Mechanism. J Biol Chem 276, 12520-16634.

 

Hwang, D. Y., Chae, K. R., Shin, D. H., Hwang, J. H., Lim, C. H., Kim, Y. J., Kim, B. J., Goo, J. S., Shin, Y. Y., Jang, I. S., et al. (2001). Xenobiotic response in humanized double transgenic mice expressing tetracycline-controlled transactivator and human CYP1B1. Arch Biochem Biophys 395, 32-40.

 

Ichikawa, K., Liu, W., Zhao, L., Wang, Z., Liu, D., Ohtsuka, T., Zhang, H., Mountz, J. D., Koopman, W. J., Kimberly, R. P., and Zhou, T. (2001). Tumoricidal activity of a novel anti-human DR5 monoclonal antibody without hepatocyte cytotoxicity. Nat Med 7, 954-960.

 

Igal, R. A., Wang, S., Gonzalez-Baro, M., and Coleman, R. A. (2001). Mitochondrial Glycerol Phosphate Acyltransferase Directs the Incorporation of Exogenous Fatty Acids into Triacylglycerol. J Biol Chem 276, 42205-44449.

 

Ishii, H., Vecchione, A., Murakumo, Y., Baldassarre, G., Numata, S., Trapasso, F., Alder, H., Baffa, R., and Croce, C. M. (2001). FEZ1/LZTS1 gene at 8p22 suppresses cancer cell growth and regulates mitosis. PNAS 98, 10374-12965.

 

Iversen, T. G., Skretting, G., Llorente, A., Nicoziani, P., van Deurs, B., and Sandvig, K. (2001). Endosome to golgi transport of ricin is independent of clathrin and of the rab9- and rab11-gtpases. Mol Biol Cell 12, 2099-2107.

 

Iwawaki, T., Hosoda, A., Okuda, T., Kamigori, Y., Nomura-Furuwatari, C., Kimata, Y., Tsuru, A., and Kohno, K. (2001). Translational control by the ER transmembrane kinase/ribonuclease IRE1 under ER stress. Nat Cell Biol 3, 158-164.

 

Jakobi, R., Moertl, E., and Koeppel, M. A. (2001). p21-activated Protein Kinase gamma -PAK Suppresses Programmed Cell Death of BALB3T3 Fibroblasts. J Biol Chem 276, 16624-16634.

 

Jannatipour, M., Dion, P., Khan, S., Jindal, H., Fan, X., Laganiere, J., Chishti, A. H., and Rouleau, G. A. (2001). Schwannomin Isoform-1 Interacts with Syntenin via PDZ Domains. J Biol Chem 276, 33093-32190.

 

Jerecic, J., Schulze, C. H., Jonas, P., Sprengel, R., Seeburg, P. H., and Bischofberger, J. (2001). Impaired NMDA receptor function in mouse olfactory bulb neurons by tetracycline-sensitive NR1 (N598R) expression. Brain Res Mol Brain Res 94, 96-104.

 

Jerome, K. R., Chen, Z., Lang, R., Torres, M. R., Hofmeister, J., Smith, S., Fox, R., Froelich, C. J., and Corey, L. (2001). HSV and Glycoprotein J Inhibit Caspase Activation and Apoptosis Induced by Granzyme B or Fas. J Immunol 167, 3928-7110.

 

Jiang, D. M., Jha, N., Boonplueang, R., and Andersen, J. K. (2001). Caspase 3 inhibition attenuates hydrogen peroxide-induced DNA fragmentation but not cell death in neuronal PC12 cells. Journal of Neurochemistry 76, 1745-1755.

 

Jiang, M., Axe, T., Holgate, R., Rubbi, C. P., Okorokov, A. L., Mee, T., and Milner, J. (2001). p53 binds the nuclear matrix in normal cells: binding involves the proline-rich domain of p53 and increases following genotoxic stress. Oncogene 20, 5449-5458.

 

Jin, Y., Blue, E. K., Dixon, S., Hou, L., Wysolmerski, R. B., and Gallagher, P. J. (2001). Identification of a New Form of Death-associated Protein Kinase That Promotes Cell Survival. J Biol Chem 276, 39667-32190.

 

Johannessen, L. E., Haugen, K. E., ostvold, A. C., Stang, E., and Madshus, I. H. (2001). Heterodimerization of the epidermal-growth-factor (EGF) receptor and ErbB2 and the affinity of EGF binding are regulated by different mechanisms. Biochem J 356, 87-96.

 

Johansen, L. M., Iwama, A., Lodie, T. A., Sasaki, K., Felsher, D. W., Golub, T. R., and Tenen, D. G. (2001). c-Myc Is a Critical Target for C/EBP{alpha} in Granulopoiesis. Mol Cell Biol 21, 3789-4828.

 

Johnstone, R. W., Gerber, M., Landewe, T., Tollefson, A., Wold, W. S., and Shilatifard, A. (2001). Functional Analysis of the Leukemia Protein ELL: Evidence for a Role in the Regulation of Cell Growth and Survival. Mol Cell Biol 21, 1672-1539.

 

Joliot, V., Goujon, C., Dumonceaux, J., Renard, A., Briand, P., and Hazan, U. (2001). A human immunodeficiency virus Env inducible transcription system to examine consequences of gp120 expression. J Virol Methods 98, 145-151.

 

Jones, N., Voskas, D., Master, Z., Sarao, R., Jones, J., and Dumont, D. J. (2001). Rescue of the early vascular defects in Tek/Tie2 null mice reveals an essential survival function. EMBO Rep 2, 438-445.

 

Jornvall, H., Blokzijl, A., Dijke, P. t., and Ibanez, C. F. (2001). The Orphan Receptor Serine/Threonine Kinase ALK7 Signals Arrest of Proliferation and Morphological Differentiation in a Neuronal Cell Line. J Biol Chem 276, 5140-16634.

 

Jost, M., Huggett, T. M., Kari, C., Boise, L. H., and Rodeck, U. (2001). Epidermal Growth Factor Receptor-dependent Control of Keratinocyte Survival and Bcl-xL Expression through a MEK-dependent Pathway. J Biol Chem 276, 6320-16634.

 

Jost, M., Gasparro, F. P., Jensen, P. J., and Rodeck, U. (2001). Keratinocyte apoptosis induced by ultraviolet B radiation and CD95 ligation -- differential protection through epidermal growth factor receptor activation and Bcl-x(L) expression. J Invest Dermatol 116, 860-866.

 

Ju, H., Gros, R., You, X., Tsang, S., Husain, M., and Rabinovitch, M. (2001). Conditional and targeted overexpression of vascular chymase causes hypertension in transgenic mice. PNAS 98, 7469-7474.

 

Jung, M. S., Yun, J., Chae, H. D., Kim, J. M., Kim, S. C., Choi, T. S., and Shin, D. Y. (2001). p53 and its homologues, p63 and p73, induce a replicative senescence through inactivation of NF-Y transcription factor. Oncogene 20, 5818-5825.

 

Kang, M.-S., Hung, S. C., and Kieff, E. (2001). Epstein-Barr virus nuclear antigen 1 activates transcription from episomal but not integrated DNA and does not alter lymphocyte growth. PNAS 98, 15233-12965.

 

Karlsen, A. E., Ronn, S. G., Lindberg, K., Johannesen, J., Galsgaard, E. D., Pociot, F., Nielsen, J. H., Mandrup-Poulsen, T., Nerup, J., and Billestrup, N. (2001). Suppressor of cytokine signaling 3 (SOCS-3) protects beta -cells against interleukin-1beta - and interferon-gamma -mediated toxicity. PNAS 98, 12191-12965.

 

Kaufmann, H., Mazur, X., Marone, R., Bailey, J. E., and Fussenegger, M. (2001). Comparative analysis of two controlled proliferation strategies regarding product quality, influence on tetracycline-regulated gene expression, and productivity. Biotechnol Bioeng 72, 592-602.

 

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Kaykas, A., Worringer, K., and Sugden, B. (2001). CD40 and LMP-1 both signal from lipid rafts but LMP-1 assembles a distinct, more efficient signaling complex. Embo J 20, 2641-2654.

 

Kazmierczak, B. I., Jou, T. S., Mostov, K., and Engel, J. N. (2001). Rho GTPase activity modulates Pseudomonas aeruginosa internalization by epithelial cells. Cell Microbiol 3, 85-98.

 

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Khan, S., de Giuli, R., Schmidtke, G., Bruns, M., Buchmeier, M., van den Broek, M., and Groettrup, M. (2001). Cutting Edge: Neosynthesis Is Required for the Presentation of a T Cell Epitope from a Long-Lived Viral Protein. J Immunol 167, 4801-7110.

 

Khanna-Gupta, A., Zibello, T., Sun, H., Lekstrom-Himes, J., and Berliner, N. (2001). C/EBPvarepsilon mediates myeloid differentiation and is regulated by the CCAAT displacement protein (CDP/cut). PNAS 98, 8000-12965.

 

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Kitamoto, T. (2001). Conditional modification of behavior in Drosophila by targeted expression of a temperature-sensitive shibire allele in defined neurons. J Neurobiol 47, 81-92.

 

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